000 01584 a2200397 4500
005 20250517113400.0
264 0 _c20170707
008 201707s 0 0 eng d
022 _a1592-8721
024 7 _a10.3324/haematol.2016.146381
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMendes, Rui D
245 0 0 _aThe relevance of PTEN-AKT in relation to NOTCH1-directed treatment strategies in T-cell acute lymphoblastic leukemia.
_h[electronic resource]
260 _bHaematologica
_c09 2016
300 _a1010-7 p.
_bdigital
500 _aPublication Type: Journal Article; Review; Research Support, Non-U.S. Gov't
650 0 4 _aAmyloid Precursor Protein Secretases
_xantagonists & inhibitors
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xtherapeutic use
650 0 4 _aDrug Resistance, Neoplasm
_xgenetics
650 0 4 _aGene Expression Regulation, Leukemic
_xdrug effects
650 0 4 _aHumans
650 0 4 _aMolecular Targeted Therapy
650 0 4 _aMutation
650 0 4 _aPTEN Phosphohydrolase
_xgenetics
650 0 4 _aPrecursor T-Cell Lymphoblastic Leukemia-Lymphoma
_xdrug therapy
650 0 4 _aProto-Oncogene Proteins c-akt
_xgenetics
650 0 4 _aReceptor, Notch1
_xgenetics
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aTumor Suppressor Proteins
_xgenetics
700 1 _aCanté-Barrett, Kirsten
700 1 _aPieters, Rob
700 1 _aMeijerink, Jules P P
773 0 _tHaematologica
_gvol. 101
_gno. 9
_gp. 1010-7
856 4 0 _uhttps://doi.org/10.3324/haematol.2016.146381
_zAvailable from publisher's website
999 _c26379569
_d26379569