000 01521 a2200397 4500
005 20250517113132.0
264 0 _c20180523
008 201805s 0 0 eng d
022 _a1520-5126
024 7 _a10.1021/jacs.6b06823
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aRenata, Hans
245 0 0 _aIdentification of Mechanism-Based Inactivation in P450-Catalyzed Cyclopropanation Facilitates Engineering of Improved Enzymes.
_h[electronic resource]
260 _bJournal of the American Chemical Society
_c09 2016
300 _a12527-33 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
650 0 4 _aAmino Acid Sequence
650 0 4 _aCatalysis
650 0 4 _aCoenzymes
650 0 4 _aCytochrome P-450 Enzyme Inhibitors
650 0 4 _aCytochrome P-450 Enzyme System
_xchemistry
650 0 4 _aEscherichia coli
_xmetabolism
650 0 4 _aHeme
650 0 4 _aModels, Molecular
650 0 4 _aMutagenesis, Site-Directed
650 0 4 _aProtein Conformation
650 0 4 _aProtein Engineering
_xmethods
700 1 _aLewis, Russell D
700 1 _aSweredoski, Michael J
700 1 _aMoradian, Annie
700 1 _aHess, Sonja
700 1 _aWang, Z Jane
700 1 _aArnold, Frances H
773 0 _tJournal of the American Chemical Society
_gvol. 138
_gno. 38
_gp. 12527-33
856 4 0 _uhttps://doi.org/10.1021/jacs.6b06823
_zAvailable from publisher's website
999 _c26371154
_d26371154