000 02450 a2200757 4500
005 20250517112848.0
264 0 _c20180917
008 201809s 0 0 eng d
022 _a2041-1723
024 7 _a10.1038/ncomms12586
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMasuda, Mari
245 0 0 _aTNIK inhibition abrogates colorectal cancer stemness.
_h[electronic resource]
260 _bNature communications
_c08 2016
300 _a12586 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdenomatous Polyposis Coli Protein
_xgenetics
650 0 4 _aAdministration, Oral
650 0 4 _aAged
650 0 4 _aAnimals
650 0 4 _aAzoxymethane
_xtoxicity
650 0 4 _aCarcinogenesis
_xdrug effects
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCell Transformation, Neoplastic
_xpathology
650 0 4 _aColorectal Neoplasms
_xchemically induced
650 0 4 _aCrystallography, X-Ray
650 0 4 _aFemale
650 0 4 _aGerminal Center Kinases
650 0 4 _aHumans
650 0 4 _aImidazoles
_xpharmacology
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Inbred BALB C
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMice, Knockout
650 0 4 _aMice, Nude
650 0 4 _aMiddle Aged
650 0 4 _aMutation
650 0 4 _aNeoplastic Stem Cells
_xdrug effects
650 0 4 _aProtein Binding
650 0 4 _aProtein Kinase Inhibitors
_xpharmacology
650 0 4 _aProtein Serine-Threonine Kinases
_xantagonists & inhibitors
650 0 4 _aQuinazolines
_xpharmacology
650 0 4 _aRecombinant Proteins
_xgenetics
650 0 4 _aUbiquitin-Protein Ligases
650 0 4 _aWnt Proteins
_xmetabolism
650 0 4 _aWnt Signaling Pathway
_xdrug effects
650 0 4 _aXenograft Model Antitumor Assays
650 0 4 _abeta Catenin
_xgenetics
700 1 _aUno, Yuko
700 1 _aOhbayashi, Naomi
700 1 _aOhata, Hirokazu
700 1 _aMimata, Ayako
700 1 _aKukimoto-Niino, Mutsuko
700 1 _aMoriyama, Hideki
700 1 _aKashimoto, Shigeki
700 1 _aInoue, Tomoko
700 1 _aGoto, Naoko
700 1 _aOkamoto, Koji
700 1 _aShirouzu, Mikako
700 1 _aSawa, Masaaki
700 1 _aYamada, Tesshi
773 0 _tNature communications
_gvol. 7
_gp. 12586
856 4 0 _uhttps://doi.org/10.1038/ncomms12586
_zAvailable from publisher's website
999 _c26361760
_d26361760