000 01619 a2200409 4500
005 20250517112249.0
264 0 _c20170216
008 201702s 0 0 eng d
022 _a1768-3254
024 7 _a10.1016/j.ejmech.2016.08.013
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLamie, Phoebe F
245 0 0 _aNovel N-substituted indole Schiff bases as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase enzymes: Synthesis, biological activities in vitro and docking study.
_h[electronic resource]
260 _bEuropean journal of medicinal chemistry
_cNov 2016
300 _a803-813 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnti-Inflammatory Agents
_xchemical synthesis
650 0 4 _aAntineoplastic Agents
_xchemical synthesis
650 0 4 _aArachidonate 5-Lipoxygenase
_xchemistry
650 0 4 _aCatalytic Domain
650 0 4 _aCell Line, Tumor
650 0 4 _aChemistry Techniques, Synthetic
650 0 4 _aCyclooxygenase 1
_xmetabolism
650 0 4 _aCyclooxygenase 2
_xmetabolism
650 0 4 _aCyclooxygenase 2 Inhibitors
_xchemical synthesis
650 0 4 _aDrug Design
650 0 4 _aHumans
650 0 4 _aIndoles
_xchemical synthesis
650 0 4 _aLipoxygenase Inhibitors
_xchemical synthesis
650 0 4 _aMolecular Docking Simulation
650 0 4 _aSchiff Bases
_xchemistry
700 1 _aAli, Waleed A M
700 1 _aBazgier, Vaclav
700 1 _aRárová, Lucie
773 0 _tEuropean journal of medicinal chemistry
_gvol. 123
_gp. 803-813
856 4 0 _uhttps://doi.org/10.1016/j.ejmech.2016.08.013
_zAvailable from publisher's website
999 _c26342893
_d26342893