000 02416 a2200661 4500
005 20250517111716.0
264 0 _c20171220
008 201712s 0 0 eng d
022 _a1096-1186
024 7 _a10.1016/j.phrs.2016.08.016
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aDruzhyna, Nadiya
245 0 0 _aScreening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer.
_h[electronic resource]
260 _bPharmacological research
_c11 2016
300 _a18-37 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
650 0 4 _aAnimals
650 0 4 _aBenserazide
_xpharmacology
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aColonic Neoplasms
_xdrug therapy
650 0 4 _aCoumarins
_xpharmacology
650 0 4 _aCystathionine beta-Synthase
_xantagonists & inhibitors
650 0 4 _aDrug Repositioning
_xmethods
650 0 4 _aEnergy Metabolism
_xdrug effects
650 0 4 _aFemale
650 0 4 _aHCT116 Cells
650 0 4 _aHT29 Cells
650 0 4 _aHumans
650 0 4 _aHydrazines
_xpharmacology
650 0 4 _aHydrogen Sulfide
_xmetabolism
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Nude
650 0 4 _aMitochondria
_xdrug effects
650 0 4 _aMorpholines
_xpharmacology
650 0 4 _aOrganothiophosphorus Compounds
_xpharmacology
650 0 4 _aTherapies, Investigational
_xmethods
700 1 _aSzczesny, Bartosz
700 1 _aOlah, Gabor
700 1 _aMódis, Katalin
700 1 _aAsimakopoulou, Antonia
700 1 _aPavlidou, Athanasia
700 1 _aSzoleczky, Petra
700 1 _aGerö, Domokos
700 1 _aYanagi, Kazunori
700 1 _aTörö, Gabor
700 1 _aLópez-García, Isabel
700 1 _aMyrianthopoulos, Vassilios
700 1 _aMikros, Emmanuel
700 1 _aZatarain, John R
700 1 _aChao, Celia
700 1 _aPapapetropoulos, Andreas
700 1 _aHellmich, Mark R
700 1 _aSzabo, Csaba
773 0 _tPharmacological research
_gvol. 113
_gno. Pt A
_gp. 18-37
856 4 0 _uhttps://doi.org/10.1016/j.phrs.2016.08.016
_zAvailable from publisher's website
999 _c26325440
_d26325440