000 02679 a2200805 4500
005 20250517105526.0
264 0 _c20160824
008 201608s 0 0 eng d
022 _a1476-4687
024 7 _a10.1038/nature18325
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aRay Chaudhuri, Arnab
245 0 0 _aReplication fork stability confers chemoresistance in BRCA-deficient cells.
_h[electronic resource]
260 _bNature
_c07 2016
300 _a382-7 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
650 0 4 _aAnimals
650 0 4 _aCarrier Proteins
_xgenetics
650 0 4 _aCell Line, Tumor
650 0 4 _aCisplatin
_xpharmacology
650 0 4 _aDNA
_xbiosynthesis
650 0 4 _aDNA Breaks, Double-Stranded
650 0 4 _aDNA Damage
_xdrug effects
650 0 4 _aDNA Helicases
_xgenetics
650 0 4 _aDNA Repair
_xdrug effects
650 0 4 _aDNA Repair Enzymes
_xantagonists & inhibitors
650 0 4 _aDNA Replication
_xdrug effects
650 0 4 _aDNA-Binding Proteins
_xantagonists & inhibitors
650 0 4 _aDrug Resistance, Neoplasm
_xdrug effects
650 0 4 _aEmbryonic Stem Cells
_xdrug effects
650 0 4 _aFemale
650 0 4 _aGene Deletion
650 0 4 _aGenes, BRCA1
650 0 4 _aGenes, BRCA2
650 0 4 _aHomologous Recombination
650 0 4 _aMRE11 Homologue Protein
650 0 4 _aMice
650 0 4 _aNeoplasms
_xgenetics
650 0 4 _aNuclear Proteins
_xdeficiency
650 0 4 _aPoly (ADP-Ribose) Polymerase-1
650 0 4 _aPoly(ADP-ribose) Polymerase Inhibitors
_xpharmacology
650 0 4 _aPoly(ADP-ribose) Polymerases
_xgenetics
700 1 _aCallen, Elsa
700 1 _aDing, Xia
700 1 _aGogola, Ewa
700 1 _aDuarte, Alexandra A
700 1 _aLee, Ji-Eun
700 1 _aWong, Nancy
700 1 _aLafarga, Vanessa
700 1 _aCalvo, Jennifer A
700 1 _aPanzarino, Nicholas J
700 1 _aJohn, Sam
700 1 _aDay, Amanda
700 1 _aCrespo, Anna Vidal
700 1 _aShen, Binghui
700 1 _aStarnes, Linda M
700 1 _ade Ruiter, Julian R
700 1 _aDaniel, Jeremy A
700 1 _aKonstantinopoulos, Panagiotis A
700 1 _aCortez, David
700 1 _aCantor, Sharon B
700 1 _aFernandez-Capetillo, Oscar
700 1 _aGe, Kai
700 1 _aJonkers, Jos
700 1 _aRottenberg, Sven
700 1 _aSharan, Shyam K
700 1 _aNussenzweig, André
773 0 _tNature
_gvol. 535
_gno. 7612
_gp. 382-7
856 4 0 _uhttps://doi.org/10.1038/nature18325
_zAvailable from publisher's website
999 _c26252028
_d26252028