000 01569 a2200421 4500
005 20250517103657.0
264 0 _c20170726
008 201707s 0 0 eng d
022 _a1464-3405
024 7 _a10.1016/j.bmcl.2016.06.070
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aStrelnik, Alexey D
245 0 0 _aNovel potent pyridoxine-based inhibitors of AChE and BChE, structural analogs of pyridostigmine, with improved in vivo safety profile.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_c08 2016
300 _a4092-4 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAcetylcholinesterase
_xchemistry
650 0 4 _aAnimals
650 0 4 _aButyrylcholinesterase
_xchemistry
650 0 4 _aCholinesterase Inhibitors
_xchemistry
650 0 4 _aLethal Dose 50
650 0 4 _aMice
650 0 4 _aProtein Binding
650 0 4 _aPyridostigmine Bromide
_xanalogs & derivatives
650 0 4 _aPyridoxine
_xchemistry
650 0 4 _aStructure-Activity Relationship
650 0 4 _aToxicity Tests, Acute
700 1 _aPetukhov, Alexey S
700 1 _aZueva, Irina V
700 1 _aZobov, Vladimir V
700 1 _aPetrov, Konstantin A
700 1 _aNikolsky, Evgeny E
700 1 _aBalakin, Konstantin V
700 1 _aBachurin, Sergey O
700 1 _aShtyrlin, Yurii G
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 26
_gno. 16
_gp. 4092-4
856 4 0 _uhttps://doi.org/10.1016/j.bmcl.2016.06.070
_zAvailable from publisher's website
999 _c26190166
_d26190166