000			02212 a2200661 4500
005			20250517101028.0
264		0	_c20170529
008			201705s 0 0 eng d
022			_a1520-4804
024	7		_a10.1021/acs.jmedchem.6b00544 _2doi
040			_aNLM _beng _cNLM
100	1		_aDavoren, Jennifer E
245	0	0	_aDiscovery of the Potent and Selective M1 PAM-Agonist N-[(3R,4S)-3-Hydroxytetrahydro-2H-pyran-4-yl]-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide (PF-06767832): Evaluation of Efficacy and Cholinergic Side Effects. _h[electronic resource]
260			_bJournal of medicinal chemistry _c07 2016
300			_a6313-28 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAnimals
650	0	4	_aDose-Response Relationship, Drug
650	0	4	_aDrug Discovery
650	0	4	_aFemale
650	0	4	_aMale
650	0	4	_aMice
650	0	4	_aModels, Molecular
650	0	4	_aMolecular Structure
650	0	4	_aPicolinic Acids _xchemical synthesis
650	0	4	_aRats
650	0	4	_aReceptor, Muscarinic M1 _xagonists
650	0	4	_aStructure-Activity Relationship
650	0	4	_aThiazoles _xchemical synthesis
700	1		_aLee, Che-Wah
700	1		_aGarnsey, Michelle
700	1		_aBrodney, Michael A
700	1		_aCordes, Jason
700	1		_aDlugolenski, Keith
700	1		_aEdgerton, Jeremy R
700	1		_aHarris, Anthony R
700	1		_aHelal, Christopher J
700	1		_aJenkinson, Stephen
700	1		_aKauffman, Gregory W
700	1		_aKenakin, Terrence P
700	1		_aLazzaro, John T
700	1		_aLotarski, Susan M
700	1		_aMao, Yuxia
700	1		_aNason, Deane M
700	1		_aNorthcott, Carrie
700	1		_aNottebaum, Lisa
700	1		_aO'Neil, Steven V
700	1		_aPettersen, Betty
700	1		_aPopiolek, Michael
700	1		_aReinhart, Veronica
700	1		_aSalomon-Ferrer, Romelia
700	1		_aSteyn, Stefanus J
700	1		_aWebb, Damien
700	1		_aZhang, Lei
700	1		_aGrimwood, Sarah
773	0		_tJournal of medicinal chemistry _gvol. 59 _gno. 13 _gp. 6313-28
856	4	0	_uhttps://doi.org/10.1021/acs.jmedchem.6b00544 _zAvailable from publisher's website
999			_c26103042 _d26103042