000 02108 a2200625 4500
005 20250517095414.0
264 0 _c20170515
008 201705s 0 0 eng d
022 _a1552-4469
024 7 _a10.1038/nchembio.2087
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aJohansson, Catrine
245 0 0 _aStructural analysis of human KDM5B guides histone demethylase inhibitor development.
_h[electronic resource]
260 _bNature chemical biology
_c07 2016
300 _a539-45 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents
_xchemistry
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aDrug Screening Assays, Antitumor
650 0 4 _aEnzyme Inhibitors
_xchemistry
650 0 4 _aHistone Demethylases
_xantagonists & inhibitors
650 0 4 _aHumans
650 0 4 _aJumonji Domain-Containing Histone Demethylases
_xchemistry
650 0 4 _aModels, Molecular
650 0 4 _aMultiple Myeloma
_xdrug therapy
650 0 4 _aNuclear Proteins
_xchemistry
650 0 4 _aProtein Conformation
650 0 4 _aRepressor Proteins
_xchemistry
650 0 4 _aStructure-Activity Relationship
700 1 _aVelupillai, Srikannathasan
700 1 _aTumber, Anthony
700 1 _aSzykowska, Aleksandra
700 1 _aHookway, Edward S
700 1 _aNowak, Radoslaw P
700 1 _aStrain-Damerell, Claire
700 1 _aGileadi, Carina
700 1 _aPhilpott, Martin
700 1 _aBurgess-Brown, Nicola
700 1 _aWu, Na
700 1 _aKopec, Jola
700 1 _aNuzzi, Andrea
700 1 _aSteuber, Holger
700 1 _aEgner, Ursula
700 1 _aBadock, Volker
700 1 _aMunro, Shonagh
700 1 _aLaThangue, Nicholas B
700 1 _aWestaway, Sue
700 1 _aBrown, Jack
700 1 _aAthanasou, Nick
700 1 _aPrinjha, Rab
700 1 _aBrennan, Paul E
700 1 _aOppermann, Udo
773 0 _tNature chemical biology
_gvol. 12
_gno. 7
_gp. 539-45
856 4 0 _uhttps://doi.org/10.1038/nchembio.2087
_zAvailable from publisher's website
999 _c26049863
_d26049863