| 000 | 02484 a2200781 4500 | ||
|---|---|---|---|
| 005 | 20250517094826.0 | ||
| 264 | 0 | _c20170523 | |
| 008 | 201705s 0 0 eng d | ||
| 022 | _a1521-0103 | ||
| 024 | 7 |
_a10.1124/jpet.116.232249 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aToyn, Jeremy H | |
| 245 | 0 | 0 |
_aRobust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects. _h[electronic resource] |
| 260 |
_bThe Journal of pharmacology and experimental therapeutics _c07 2016 |
||
| 300 |
_a125-37 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 |
_aAmyloid Precursor Protein Secretases _xmetabolism |
| 650 | 0 | 4 |
_aAmyloid beta-Peptides _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aAniline Compounds _xchemistry |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aBrain _xdrug effects |
| 650 | 0 | 4 |
_aBridged-Ring Compounds _xchemistry |
| 650 | 0 | 4 | _aCell Line |
| 650 | 0 | 4 | _aDogs |
| 650 | 0 | 4 | _aDose-Response Relationship, Drug |
| 650 | 0 | 4 | _aDrug Evaluation, Preclinical |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMacaca fascicularis |
| 650 | 0 | 4 |
_aPyrimidines _xchemistry |
| 650 | 0 | 4 | _aRats, Sprague-Dawley |
| 650 | 0 | 4 |
_aReceptors, Notch _xmetabolism |
| 650 | 0 | 4 | _aSpecies Specificity |
| 650 | 0 | 4 | _aTissue Distribution |
| 700 | 1 | _aBoy, Kenneth M | |
| 700 | 1 | _aRaybon, Joseph | |
| 700 | 1 | _aMeredith, Jere E | |
| 700 | 1 | _aRobertson, Alan S | |
| 700 | 1 | _aGuss, Valerie | |
| 700 | 1 | _aHoque, Nina | |
| 700 | 1 | _aSweeney, Francis | |
| 700 | 1 | _aZhuo, Xiaoliang | |
| 700 | 1 | _aClarke, Wendy | |
| 700 | 1 | _aSnow, Kimberly | |
| 700 | 1 | _aDenton, R Rex | |
| 700 | 1 | _aZuev, Dmitry | |
| 700 | 1 | _aThompson, Lorin A | |
| 700 | 1 | _aMorrison, John | |
| 700 | 1 | _aGrace, James | |
| 700 | 1 | _aBerisha, Flora | |
| 700 | 1 | _aFurlong, Michael | |
| 700 | 1 | _aWang, Jun-Sheng | |
| 700 | 1 | _aLentz, Kimberly A | |
| 700 | 1 | _aPadmanabha, Ramesh | |
| 700 | 1 | _aCook, Lynda | |
| 700 | 1 | _aWei, Cong | |
| 700 | 1 | _aDrexler, Dieter M | |
| 700 | 1 | _aMacor, John E | |
| 700 | 1 | _aAlbright, Charlie F | |
| 700 | 1 | _aGasior, Maciej | |
| 700 | 1 | _aOlson, Richard E | |
| 700 | 1 | _aHong, Quan | |
| 700 | 1 | _aSoares, Holly D | |
| 700 | 1 | _aAbuTarif, Malaz | |
| 700 | 1 | _aAhlijanian, Michael K | |
| 773 | 0 |
_tThe Journal of pharmacology and experimental therapeutics _gvol. 358 _gno. 1 _gp. 125-37 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1124/jpet.116.232249 _zAvailable from publisher's website |
| 999 |
_c26029787 _d26029787 |
||