000 01905 a2200529 4500
005 20250517093935.0
264 0 _c20170913
008 201709s 0 0 eng d
022 _a1558-8238
024 7 _a10.1172/JCI85183
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLock, Rebecca
245 0 0 _aCotargeting MNK and MEK kinases induces the regression of NF1-mutant cancers.
_h[electronic resource]
260 _bThe Journal of clinical investigation
_c06 2016
300 _a2181-90 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnilides
_xadministration & dosage
650 0 4 _aAnimals
650 0 4 _aCell Line, Tumor
650 0 4 _aGenes, Neurofibromatosis 1
650 0 4 _aHumans
650 0 4 _aMAP Kinase Kinase Kinases
_xantagonists & inhibitors
650 0 4 _aMechanistic Target of Rapamycin Complex 1
650 0 4 _aMice
650 0 4 _aMultiprotein Complexes
_xmetabolism
650 0 4 _aMutation
650 0 4 _aNerve Sheath Neoplasms
_xdrug therapy
650 0 4 _aNeurofibromin 1
_xgenetics
650 0 4 _aNucleocytoplasmic Transport Proteins
_xantagonists & inhibitors
650 0 4 _aPhosphorylation
650 0 4 _aProtein Kinase Inhibitors
_xadministration & dosage
650 0 4 _aProtein Serine-Threonine Kinases
_xantagonists & inhibitors
650 0 4 _aPyridines
_xadministration & dosage
650 0 4 _aSignal Transduction
650 0 4 _aTOR Serine-Threonine Kinases
_xmetabolism
700 1 _aIngraham, Rachel
700 1 _aMaertens, Ophélia
700 1 _aMiller, Abigail L
700 1 _aWeledji, Nelly
700 1 _aLegius, Eric
700 1 _aKonicek, Bruce M
700 1 _aYan, Sau-Chi B
700 1 _aGraff, Jeremy R
700 1 _aCichowski, Karen
773 0 _tThe Journal of clinical investigation
_gvol. 126
_gno. 6
_gp. 2181-90
856 4 0 _uhttps://doi.org/10.1172/JCI85183
_zAvailable from publisher's website
999 _c26001311
_d26001311