| 000 | 01468 a2200421 4500 | ||
|---|---|---|---|
| 005 | 20250517093502.0 | ||
| 264 | 0 | _c20170731 | |
| 008 | 201707s 0 0 eng d | ||
| 022 | _a1549-960X | ||
| 024 | 7 |
_a10.1021/acs.jcim.5b00641 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aRobinson, Daniel | |
| 245 | 0 | 0 |
_aDifferential Water Thermodynamics Determine PI3K-Beta/Delta Selectivity for Solvent-Exposed Ligand Modifications. _h[electronic resource] |
| 260 |
_bJournal of chemical information and modeling _c05 2016 |
||
| 300 |
_a886-94 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aLigands |
| 650 | 0 | 4 | _aMolecular Dynamics Simulation |
| 650 | 0 | 4 |
_aPhosphatidylinositol 3-Kinases _xchemistry |
| 650 | 0 | 4 | _aProtein Conformation |
| 650 | 0 | 4 |
_aProtein Subunits _xchemistry |
| 650 | 0 | 4 |
_aSolvents _xchemistry |
| 650 | 0 | 4 | _aSubstrate Specificity |
| 650 | 0 | 4 | _aThermodynamics |
| 650 | 0 | 4 |
_aWater _xchemistry |
| 700 | 1 | _aBertrand, Thomas | |
| 700 | 1 | _aCarry, Jean-Christophe | |
| 700 | 1 | _aHalley, Frank | |
| 700 | 1 | _aKarlsson, Andreas | |
| 700 | 1 | _aMathieu, Magali | |
| 700 | 1 | _aMinoux, Hervé | |
| 700 | 1 | _aPerrin, Marc-Antoine | |
| 700 | 1 | _aRobert, Benoit | |
| 700 | 1 | _aSchio, Laurent | |
| 700 | 1 | _aSherman, Woody | |
| 773 | 0 |
_tJournal of chemical information and modeling _gvol. 56 _gno. 5 _gp. 886-94 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/acs.jcim.5b00641 _zAvailable from publisher's website |
| 999 |
_c25987089 _d25987089 |
||