000			02143 a2200625 4500
005			20250517084340.0
264		0	_c20170213
008			201702s 0 0 eng d
022			_a1872-7980
024	7		_a10.1016/j.canlet.2016.03.013 _2doi
040			_aNLM _beng _cNLM
100	1		_aQin, Xiaoyu
245	0	0	_aGankyrin activates mTORC1 signaling by accelerating TSC2 degradation in colorectal cancer. _h[electronic resource]
260			_bCancer letters _c06 2016
300			_a83-94 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAnimals
650	0	4	_aCell Line, Tumor
650	0	4	_aCell Proliferation
650	0	4	_aColorectal Neoplasms _xenzymology
650	0	4	_aEnzyme Activation
650	0	4	_aGene Expression Regulation, Enzymologic
650	0	4	_aGene Expression Regulation, Neoplastic
650	0	4	_aHeterografts
650	0	4	_aHumans
650	0	4	_aKaplan-Meier Estimate
650	0	4	_aMechanistic Target of Rapamycin Complex 1
650	0	4	_aMice, Inbred BALB C
650	0	4	_aMice, Nude
650	0	4	_aMonomeric GTP-Binding Proteins _xmetabolism
650	0	4	_aMultiprotein Complexes _xmetabolism
650	0	4	_aNeoplasm Transplantation
650	0	4	_aNeuropeptides _xmetabolism
650	0	4	_aPrognosis
650	0	4	_aProteasome Endopeptidase Complex _xgenetics
650	0	4	_aProteolysis
650	0	4	_aProto-Oncogene Proteins _xgenetics
650	0	4	_aRas Homolog Enriched in Brain Protein
650	0	4	_aSignal Transduction
650	0	4	_aTOR Serine-Threonine Kinases _xmetabolism
650	0	4	_aTime Factors
650	0	4	_aTransfection
650	0	4	_aTuberous Sclerosis Complex 2 Protein
650	0	4	_aTumor Burden
650	0	4	_aTumor Suppressor Proteins _xmetabolism
650	0	4	_aUp-Regulation
700	1		_aWang, Xinxin
700	1		_aLiu, Feng
700	1		_aMorris, Laura E
700	1		_aWang, Xiaowen
700	1		_aJiang, Bin
700	1		_aZhang, Yanjie
773	0		_tCancer letters _gvol. 376 _gno. 1 _gp. 83-94
856	4	0	_uhttps://doi.org/10.1016/j.canlet.2016.03.013 _zAvailable from publisher's website
999			_c25826308 _d25826308