000			02054 a2200589 4500
005			20250517083553.0
264		0	_c20161213
008			201612s 0 0 eng d
022			_a1464-3405
024	7		_a10.1016/j.bmcl.2016.02.075 _2doi
040			_aNLM _beng _cNLM
100	1		_aFairhurst, Robin A
245	0	0	_aOptimisation of a 5-[3-phenyl-(2-cyclic-ether)-methyl-ether]-4-aminopyrrolopyrimidine series of IGF-1R inhibitors. _h[electronic resource]
260			_bBioorganic & medicinal chemistry letters _cApr 2016
300			_a2057-64 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAnimals
650	0	4	_aAntineoplastic Agents _xchemical synthesis
650	0	4	_aCell Proliferation _xdrug effects
650	0	4	_aDose-Response Relationship, Drug
650	0	4	_aHumans
650	0	4	_aImidazoles _xchemical synthesis
650	0	4	_aMice
650	0	4	_aMice, Nude
650	0	4	_aMolecular Structure
650	0	4	_aNIH 3T3 Cells
650	0	4	_aNeoplasms, Experimental _xdrug therapy
650	0	4	_aProtein Kinase Inhibitors _xchemical synthesis
650	0	4	_aPyrazines _xchemical synthesis
650	0	4	_aPyrimidines _xchemical synthesis
650	0	4	_aPyrroles _xchemical synthesis
650	0	4	_aReceptor, IGF Type 1 _xantagonists & inhibitors
650	0	4	_aStructure-Activity Relationship
650	0	4	_aXenograft Model Antitumor Assays
700	1		_aMarsilje, Thomas H
700	1		_aStutz, Stefan
700	1		_aBoos, Andreas
700	1		_aNiklaus, Michel
700	1		_aChen, Bei
700	1		_aJiang, Songchun
700	1		_aLu, Wenshuo
700	1		_aFuret, Pascal
700	1		_aMcCarthy, Clive
700	1		_aStauffer, Frédéric
700	1		_aGuagnano, Vito
700	1		_aVaupel, Andrea
700	1		_aMichellys, Pierre-Yves
700	1		_aSchnell, Christian
700	1		_aJeay, Sébastien
773	0		_tBioorganic & medicinal chemistry letters _gvol. 26 _gno. 8 _gp. 2057-64
856	4	0	_uhttps://doi.org/10.1016/j.bmcl.2016.02.075 _zAvailable from publisher's website
999			_c25803933 _d25803933