| 000 | 01778 a2200433 4500 | ||
|---|---|---|---|
| 005 | 20250517082540.0 | ||
| 264 | 0 | _c20170613 | |
| 008 | 201706s 0 0 eng d | ||
| 022 | _a1096-0007 | ||
| 024 | 7 |
_a10.1016/j.exer.2016.02.004 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aRen, Xinyi | |
| 245 | 0 | 0 |
_aIBI302, a promising candidate for AMD treatment, targeting both the VEGF and complement system with high binding affinity in vitro and effective targeting of the ocular tissue in healthy rhesus monkeys. _h[electronic resource] |
| 260 |
_bExperimental eye research _c04 2016 |
||
| 300 |
_a352-358 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 |
_aAngiogenesis Inhibitors _xpharmacokinetics |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aAntibodies, Monoclonal, Humanized _xtherapeutic use |
| 650 | 0 | 4 |
_aCell Proliferation _xdrug effects |
| 650 | 0 | 4 |
_aComplement Activation _xdrug effects |
| 650 | 0 | 4 |
_aComplement Inactivating Agents _xpharmacokinetics |
| 650 | 0 | 4 |
_aComplement System Proteins _xmetabolism |
| 650 | 0 | 4 |
_aHuman Umbilical Vein Endothelial Cells _xdrug effects |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aImmunoglobulin Fc Fragments _xpharmacology |
| 650 | 0 | 4 | _aIntravitreal Injections |
| 650 | 0 | 4 | _aMacaca mulatta |
| 650 | 0 | 4 |
_aMacular Degeneration _xdrug therapy |
| 650 | 0 | 4 |
_aRecombinant Fusion Proteins _xpharmacokinetics |
| 650 | 0 | 4 |
_aVascular Endothelial Growth Factor A _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aVitreous Body _xmetabolism |
| 700 | 1 | _aLi, Jia | |
| 700 | 1 | _aXu, Xianxing | |
| 700 | 1 | _aWang, Chunming | |
| 700 | 1 | _aCheng, Yuanguo | |
| 773 | 0 |
_tExperimental eye research _gvol. 145 _gp. 352-358 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.exer.2016.02.004 _zAvailable from publisher's website |
| 999 |
_c25774043 _d25774043 |
||