000 | 02491 a2200697 4500 | ||
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005 | 20250517081450.0 | ||
264 | 0 | _c20160315 | |
008 | 201603s 0 0 eng d | ||
022 | _a1476-4687 | ||
024 | 7 |
_a10.1038/nature16963 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aNishikawa, Joy L | |
245 | 0 | 0 |
_aInhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction. _h[electronic resource] |
260 |
_bNature _cFeb 2016 |
||
300 |
_a485-9 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aAntifungal Agents _xpharmacology |
650 | 0 | 4 |
_aBinding Sites _xdrug effects |
650 | 0 | 4 |
_aCandida glabrata _xdrug effects |
650 | 0 | 4 |
_aCandidiasis _xdrug therapy |
650 | 0 | 4 |
_aDNA-Binding Proteins _xgenetics |
650 | 0 | 4 |
_aDrug Resistance, Fungal _xdrug effects |
650 | 0 | 4 |
_aDrug Resistance, Multiple, Fungal _xdrug effects |
650 | 0 | 4 |
_aFluconazole _xpharmacology |
650 | 0 | 4 |
_aFungal Proteins _xmetabolism |
650 | 0 | 4 |
_aGene Expression Regulation, Fungal _xdrug effects |
650 | 0 | 4 |
_aHydrazines _xpharmacokinetics |
650 | 0 | 4 |
_aKetoconazole _xpharmacology |
650 | 0 | 4 |
_aMediator Complex _xchemistry |
650 | 0 | 4 | _aMice |
650 | 0 | 4 | _aModels, Molecular |
650 | 0 | 4 | _aNuclear Magnetic Resonance, Biomolecular |
650 | 0 | 4 |
_aProtein Binding _xdrug effects |
650 | 0 | 4 | _aProtein Structure, Tertiary |
650 | 0 | 4 |
_aSaccharomyces cerevisiae Proteins _xchemistry |
650 | 0 | 4 |
_aThiourea _xanalogs & derivatives |
650 | 0 | 4 |
_aTrans-Activators _xchemistry |
650 | 0 | 4 |
_aTranscription Factors _xgenetics |
650 | 0 | 4 |
_aTranscriptional Activation _xdrug effects |
650 | 0 | 4 |
_aUp-Regulation _xdrug effects |
700 | 1 | _aBoeszoermenyi, Andras | |
700 | 1 | _aVale-Silva, Luis A | |
700 | 1 | _aTorelli, Riccardo | |
700 | 1 | _aPosteraro, Brunella | |
700 | 1 | _aSohn, Yoo-Jin | |
700 | 1 | _aJi, Fei | |
700 | 1 | _aGelev, Vladimir | |
700 | 1 | _aSanglard, Dominique | |
700 | 1 | _aSanguinetti, Maurizio | |
700 | 1 | _aSadreyev, Ruslan I | |
700 | 1 | _aMukherjee, Goutam | |
700 | 1 | _aBhyravabhotla, Jayaram | |
700 | 1 | _aBuhrlage, Sara J | |
700 | 1 | _aGray, Nathanael S | |
700 | 1 | _aWagner, Gerhard | |
700 | 1 | _aNäär, Anders M | |
700 | 1 | _aArthanari, Haribabu | |
773 | 0 |
_tNature _gvol. 530 _gno. 7591 _gp. 485-9 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1038/nature16963 _zAvailable from publisher's website |
999 |
_c25742360 _d25742360 |