000 01699 a2200457 4500
005 20250517081229.0
264 0 _c20161226
008 201612s 0 0 eng d
022 _a2045-2322
024 7 _a10.1038/srep19976
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aCalcaterra, Nicholas E
245 0 0 _aSchizophrenia-Associated hERG channel Kv11.1-3.1 Exhibits a Unique Trafficking Deficit that is Rescued Through Proteasome Inhibition for High Throughput Screening.
_h[electronic resource]
260 _bScientific reports
_cFeb 2016
300 _a19976 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aBortezomib
_xpharmacology
650 0 4 _aCell Membrane
_xmetabolism
650 0 4 _aDrug Discovery
650 0 4 _aEther-A-Go-Go Potassium Channels
_xchemistry
650 0 4 _aGene Expression
650 0 4 _aHEK293 Cells
650 0 4 _aHigh-Throughput Screening Assays
650 0 4 _aHumans
650 0 4 _aIntracellular Space
_xmetabolism
650 0 4 _aLeupeptins
_xpharmacology
650 0 4 _aMutation
650 0 4 _aProteasome Endopeptidase Complex
_xmetabolism
650 0 4 _aProteasome Inhibitors
_xpharmacology
650 0 4 _aProtein Interaction Domains and Motifs
650 0 4 _aProtein Isoforms
650 0 4 _aProtein Transport
650 0 4 _aSchizophrenia
_xgenetics
700 1 _aHoeppner, Daniel J
700 1 _aWei, Huijun
700 1 _aJaffe, Andrew E
700 1 _aMaher, Brady J
700 1 _aBarrow, James C
773 0 _tScientific reports
_gvol. 6
_gp. 19976
856 4 0 _uhttps://doi.org/10.1038/srep19976
_zAvailable from publisher's website
999 _c25735234
_d25735234