000			01940 a2200577 4500
005			20250517080704.0
264		0	_c20160224
008			201602s 0 0 eng d
022			_a1476-4687
024	7		_a10.1038/nature16936 _2doi
040			_aNLM _beng _cNLM
100	1		_aLi, Hao
245	0	0	_aStructure- and function-based design of Plasmodium-selective proteasome inhibitors. _h[electronic resource]
260			_bNature _cFeb 2016
300			_a233-6 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650	0	4	_aAnimals
650	0	4	_aAntimalarials _xadverse effects
650	0	4	_aArtemisinins _xpharmacology
650	0	4	_aCatalytic Domain
650	0	4	_aCryoelectron Microscopy
650	0	4	_aDose-Response Relationship, Drug
650	0	4	_aDrug Design
650	0	4	_aDrug Resistance
650	0	4	_aDrug Synergism
650	0	4	_aEnzyme Activation
650	0	4	_aFemale
650	0	4	_aHumans
650	0	4	_aMice
650	0	4	_aMice, Inbred BALB C
650	0	4	_aModels, Molecular
650	0	4	_aPlasmodium _xdrug effects
650	0	4	_aPlasmodium chabaudi _xdrug effects
650	0	4	_aPlasmodium falciparum _xdrug effects
650	0	4	_aProteasome Endopeptidase Complex _xchemistry
650	0	4	_aProteasome Inhibitors _xadverse effects
650	0	4	_aProtein Subunits _xantagonists & inhibitors
650	0	4	_aSpecies Specificity
650	0	4	_aSubstrate Specificity _xdrug effects
700	1		_aO'Donoghue, Anthony J
700	1		_avan der Linden, Wouter A
700	1		_aXie, Stanley C
700	1		_aYoo, Euna
700	1		_aFoe, Ian T
700	1		_aTilley, Leann
700	1		_aCraik, Charles S
700	1		_ada Fonseca, Paula C A
700	1		_aBogyo, Matthew
773	0		_tNature _gvol. 530 _gno. 7589 _gp. 233-6
856	4	0	_uhttps://doi.org/10.1038/nature16936 _zAvailable from publisher's website
999			_c25720670 _d25720670