000 02326 a2200613 4500
005 20250517080614.0
264 0 _c20161011
008 201610s 0 0 eng d
022 _a1475-2840
024 7 _a10.1186/s12933-016-0344-2
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBakhashab, Sherin
245 0 0 _aMetformin improves the angiogenic potential of human CD34⁺ cells co-incident with downregulating CXCL10 and TIMP1 gene expression and increasing VEGFA under hyperglycemia and hypoxia within a therapeutic window for myocardial infarction.
_h[electronic resource]
260 _bCardiovascular diabetology
_cFeb 2016
300 _a27 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAngiogenesis Inducing Agents
_xpharmacology
650 0 4 _aAntigens, CD34
_xmetabolism
650 0 4 _aBiomarkers
_xmetabolism
650 0 4 _aCell Hypoxia
650 0 4 _aCells, Cultured
650 0 4 _aChemokine CXCL10
_xgenetics
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDown-Regulation
650 0 4 _aGene Expression Profiling
650 0 4 _aHuman Umbilical Vein Endothelial Cells
_xdrug effects
650 0 4 _aHumans
650 0 4 _aHyperglycemia
_xdrug therapy
650 0 4 _aHypoglycemic Agents
_xpharmacology
650 0 4 _aMembrane Proteins
_xgenetics
650 0 4 _aMetformin
_xpharmacology
650 0 4 _aMyocardial Infarction
_xdrug therapy
650 0 4 _aNeovascularization, Physiologic
_xdrug effects
650 0 4 _aOxidoreductases
_xgenetics
650 0 4 _aPhenotype
650 0 4 _aStem Cells
_xdrug effects
650 0 4 _aTissue Inhibitor of Metalloproteinase-1
_xgenetics
650 0 4 _aUp-Regulation
650 0 4 _aVascular Endothelial Growth Factor A
_xgenetics
700 1 _aAhmed, Fahad W
700 1 _aSchulten, Hans-Juergen
700 1 _aBashir, Ayat
700 1 _aKarim, Sajjad
700 1 _aAl-Malki, Abdulrahman L
700 1 _aGari, Mamdooh A
700 1 _aAbuzenadah, Adel M
700 1 _aChaudhary, Adeel G
700 1 _aAlqahtani, Mohammed H
700 1 _aLary, Sahira
700 1 _aAhmed, Farid
700 1 _aWeaver, Jolanta U
773 0 _tCardiovascular diabetology
_gvol. 15
_gp. 27
856 4 0 _uhttps://doi.org/10.1186/s12933-016-0344-2
_zAvailable from publisher's website
999 _c25718228
_d25718228