000 01219 a2200289 4500
005 20250517071503.0
264 0 _c20160815
008 201608s 0 0 eng d
022 _a1091-6490
024 7 _a10.1073/pnas.1512952113
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBolduc, David M
245 0 0 _aNicastrin functions to sterically hinder γ-secretase-substrate interactions driven by substrate transmembrane domain.
_h[electronic resource]
260 _bProceedings of the National Academy of Sciences of the United States of America
_cFeb 2016
300 _aE509-18 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural
650 0 4 _aAmyloid Precursor Protein Secretases
_xmetabolism
650 0 4 _aLipid Bilayers
650 0 4 _aMembrane Glycoproteins
_xphysiology
650 0 4 _aSubstrate Specificity
700 1 _aMontagna, Daniel R
700 1 _aGu, Yongli
700 1 _aSelkoe, Dennis J
700 1 _aWolfe, Michael S
773 0 _tProceedings of the National Academy of Sciences of the United States of America
_gvol. 113
_gno. 5
_gp. E509-18
856 4 0 _uhttps://doi.org/10.1073/pnas.1512952113
_zAvailable from publisher's website
999 _c25571309
_d25571309