| 000 | 01686 a2200421 4500 | ||
|---|---|---|---|
| 005 | 20250517070523.0 | ||
| 264 | 0 | _c20160811 | |
| 008 | 201608s 0 0 eng d | ||
| 022 | _a1091-6490 | ||
| 024 | 7 |
_a10.1073/pnas.1521919112 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aZhao, Jinghui | |
| 245 | 0 | 0 |
_amTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy. _h[electronic resource] |
| 260 |
_bProceedings of the National Academy of Sciences of the United States of America _cDec 2015 |
||
| 300 |
_a15790-7 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 | _aAutophagy |
| 650 | 0 | 4 | _aBlotting, Western |
| 650 | 0 | 4 | _aCells, Cultured |
| 650 | 0 | 4 | _aHEK293 Cells |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aHydroxymethylglutaryl-CoA Synthase _xmetabolism |
| 650 | 0 | 4 |
_aImmunosuppressive Agents _xpharmacology |
| 650 | 0 | 4 |
_aNaphthyridines _xpharmacology |
| 650 | 0 | 4 |
_aProteasome Endopeptidase Complex _xmetabolism |
| 650 | 0 | 4 |
_aProteolysis _xdrug effects |
| 650 | 0 | 4 |
_aSirolimus _xpharmacology |
| 650 | 0 | 4 |
_aTOR Serine-Threonine Kinases _xantagonists & inhibitors |
| 650 | 0 | 4 | _aTime Factors |
| 650 | 0 | 4 |
_aUbiquitin _xmetabolism |
| 650 | 0 | 4 |
_aUbiquitination _xdrug effects |
| 700 | 1 | _aZhai, Bo | |
| 700 | 1 | _aGygi, Steven P | |
| 700 | 1 | _aGoldberg, Alfred Lewis | |
| 773 | 0 |
_tProceedings of the National Academy of Sciences of the United States of America _gvol. 112 _gno. 52 _gp. 15790-7 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1073/pnas.1521919112 _zAvailable from publisher's website |
| 999 |
_c25543455 _d25543455 |
||