000 02234 a2200601 4500
005 20250517065501.0
264 0 _c20160706
008 201607s 0 0 eng d
022 _a1083-351X
024 7 _a10.1074/jbc.M115.703710
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHirata, Yasuko
245 0 0 _aInteraction between a Domain of the Negative Regulator of the Ras-ERK Pathway, SPRED1 Protein, and the GTPase-activating Protein-related Domain of Neurofibromin Is Implicated in Legius Syndrome and Neurofibromatosis Type 1.
_h[electronic resource]
260 _bThe Journal of biological chemistry
_cFeb 2016
300 _a3124-34 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdaptor Proteins, Signal Transducing
650 0 4 _aAmino Acid Transport System A
650 0 4 _aCafe-au-Lait Spots
_xgenetics
650 0 4 _aEpidermal Growth Factor
_xmetabolism
650 0 4 _aFemale
650 0 4 _aGenes, Reporter
650 0 4 _aGenetic Association Studies
650 0 4 _aHEK293 Cells
650 0 4 _aHumans
650 0 4 _aIntracellular Signaling Peptides and Proteins
_xchemistry
650 0 4 _aKinetics
650 0 4 _aMAP Kinase Signaling System
650 0 4 _aMale
650 0 4 _aMembrane Proteins
_xchemistry
650 0 4 _aModels, Molecular
650 0 4 _aMutation, Missense
650 0 4 _aNeurofibromatosis 1
_xgenetics
650 0 4 _aNeurofibromin 1
_xchemistry
650 0 4 _aPeptide Fragments
_xchemistry
650 0 4 _aPoint Mutation
650 0 4 _aProtein Conformation
650 0 4 _aProtein Interaction Domains and Motifs
650 0 4 _aProto-Oncogene Proteins p21(ras)
_xagonists
650 0 4 _aRecombinant Fusion Proteins
_xchemistry
700 1 _aBrems, Hilde
700 1 _aSuzuki, Mayu
700 1 _aKanamori, Mitsuhiro
700 1 _aOkada, Masahiro
700 1 _aMorita, Rimpei
700 1 _aLlano-Rivas, Isabel
700 1 _aOse, Toyoyuki
700 1 _aMessiaen, Ludwine
700 1 _aLegius, Eric
700 1 _aYoshimura, Akihiko
773 0 _tThe Journal of biological chemistry
_gvol. 291
_gno. 7
_gp. 3124-34
856 4 0 _uhttps://doi.org/10.1074/jbc.M115.703710
_zAvailable from publisher's website
999 _c25512851
_d25512851