000 02325 a2200685 4500
005 20250517065129.0
264 0 _c20161107
008 201611s 0 0 eng d
022 _a1949-2553
024 7 _a10.18632/oncotarget.6392
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aValletta, Simona
245 0 0 _aASXL1 mutation correction by CRISPR/Cas9 restores gene function in leukemia cells and increases survival in mouse xenografts.
_h[electronic resource]
260 _bOncotarget
_cDec 2015
300 _a44061-71 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aBase Sequence
650 0 4 _aCRISPR-Associated Proteins
_xgenetics
650 0 4 _aCRISPR-Cas Systems
650 0 4 _aCell Differentiation
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
650 0 4 _aClustered Regularly Interspaced Short Palindromic Repeats
650 0 4 _aCodon, Nonsense
650 0 4 _aGene Expression Regulation, Leukemic
650 0 4 _aGenetic Predisposition to Disease
650 0 4 _aHeterografts
650 0 4 _aHomozygote
650 0 4 _aHumans
650 0 4 _aInterleukin Receptor Common gamma Subunit
_xdeficiency
650 0 4 _aLeukemia, Myelogenous, Chronic, BCR-ABL Positive
_xgenetics
650 0 4 _aMice, Inbred NOD
650 0 4 _aMice, Knockout
650 0 4 _aMice, SCID
650 0 4 _aMolecular Sequence Data
650 0 4 _aNeoplasm Transplantation
650 0 4 _aPhenotype
650 0 4 _aPolycomb Repressive Complex 2
_xgenetics
650 0 4 _aRepressor Proteins
_xgenetics
650 0 4 _aTime Factors
650 0 4 _aTumor Suppressor Proteins
_xgenetics
650 0 4 _aUbiquitin Thiolesterase
_xgenetics
700 1 _aDolatshad, Hamid
700 1 _aBartenstein, Matthias
700 1 _aYip, Bon Ham
700 1 _aBello, Erica
700 1 _aGordon, Shanisha
700 1 _aYu, Yiting
700 1 _aShaw, Jacqueline
700 1 _aRoy, Swagata
700 1 _aScifo, Laura
700 1 _aSchuh, Anna
700 1 _aPellagatti, Andrea
700 1 _aFulga, Tudor A
700 1 _aVerma, Amit
700 1 _aBoultwood, Jacqueline
773 0 _tOncotarget
_gvol. 6
_gno. 42
_gp. 44061-71
856 4 0 _uhttps://doi.org/10.18632/oncotarget.6392
_zAvailable from publisher's website
999 _c25501754
_d25501754