000 02273 a2200637 4500
005 20250517064630.0
264 0 _c20160518
008 201605s 0 0 eng d
022 _a1550-6606
024 7 _a10.4049/jimmunol.1403099
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aPark, Jihye
245 0 0 _aThe DNA Ligase IV Syndrome R278H Mutation Impairs B Lymphopoiesis via Error-Prone Nonhomologous End-Joining.
_h[electronic resource]
260 _bJournal of immunology (Baltimore, Md. : 1950)
_cJan 2016
300 _a244-55 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aApoptosis
_xgenetics
650 0 4 _aB-Lymphocytes
_ximmunology
650 0 4 _aBase Sequence
650 0 4 _aCell Proliferation
650 0 4 _aCells, Cultured
650 0 4 _aCytidine Deaminase
_xmetabolism
650 0 4 _aDNA Breaks, Double-Stranded
650 0 4 _aDNA End-Joining Repair
_xgenetics
650 0 4 _aDNA Ligase ATP
650 0 4 _aDNA Ligases
_xgenetics
650 0 4 _aDisease Models, Animal
650 0 4 _aEczema
_xgenetics
650 0 4 _aFacies
650 0 4 _aGene Knock-In Techniques
650 0 4 _aGrowth Disorders
_xgenetics
650 0 4 _aHumans
650 0 4 _aImmunoglobulin A
_xblood
650 0 4 _aImmunoglobulin Class Switching
_xgenetics
650 0 4 _aImmunoglobulin E
_xblood
650 0 4 _aImmunoglobulin G
_xblood
650 0 4 _aImmunoglobulin Variable Region
_xgenetics
650 0 4 _aImmunoglobulins
_xgenetics
650 0 4 _aIntellectual Disability
_xgenetics
650 0 4 _aLymphopoiesis
_xgenetics
650 0 4 _aMice
650 0 4 _aMice, Knockout
650 0 4 _aMicrocephaly
_xgenetics
650 0 4 _aMolecular Sequence Data
650 0 4 _aSevere Combined Immunodeficiency
_xgenetics
650 0 4 _aTumor Suppressor Protein p53
_xgenetics
700 1 _aWelner, Robert S
700 1 _aChan, Mei-Yee
700 1 _aTroppito, Logan
700 1 _aStaber, Philipp B
700 1 _aTenen, Daniel G
700 1 _aYan, Catherine T
773 0 _tJournal of immunology (Baltimore, Md. : 1950)
_gvol. 196
_gno. 1
_gp. 244-55
856 4 0 _uhttps://doi.org/10.4049/jimmunol.1403099
_zAvailable from publisher's website
999 _c25487404
_d25487404