000 02002 a2200589 4500
005 20250517062910.0
264 0 _c20160819
008 201608s 0 0 eng d
022 _a1471-2407
024 7 _a10.1186/s12885-015-1900-y
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aZhu, Yan
245 0 0 _aDual PI3K/mTOR inhibitor BEZ235 exerts extensive antitumor activity in HER2-positive gastric cancer.
_h[electronic resource]
260 _bBMC cancer
_cNov 2015
300 _a894 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aCell Cycle
_xdrug effects
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aDisease Models, Animal
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Resistance, Neoplasm
650 0 4 _aG1 Phase Cell Cycle Checkpoints
_xdrug effects
650 0 4 _aHumans
650 0 4 _aImidazoles
_xpharmacology
650 0 4 _aMice
650 0 4 _aPhosphoinositide-3 Kinase Inhibitors
650 0 4 _aQuinolines
_xpharmacology
650 0 4 _aReceptor, ErbB-2
_xmetabolism
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aStomach Neoplasms
_xdrug therapy
650 0 4 _aTOR Serine-Threonine Kinases
_xantagonists & inhibitors
650 0 4 _aTrastuzumab
_xpharmacology
650 0 4 _aTumor Burden
_xdrug effects
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aTian, Tiantian
700 1 _aZou, Jianling
700 1 _aWang, Qiwei
700 1 _aLi, Zhongwu
700 1 _aLi, Yanyan
700 1 _aLiu, Xijuan
700 1 _aDong, Bin
700 1 _aLi, Na
700 1 _aGao, Jing
700 1 _aShen, Lin
773 0 _tBMC cancer
_gvol. 15
_gp. 894
856 4 0 _uhttps://doi.org/10.1186/s12885-015-1900-y
_zAvailable from publisher's website
999 _c25441409
_d25441409