000			02204 a2200637 4500
005			20250517060853.0
264		0	_c20160811
008			201608s 0 0 eng d
022			_a1464-3405
024	7		_a10.1016/j.bmcl.2015.10.031 _2doi
040			_aNLM _beng _cNLM
100	1		_aBoy, Kenneth M
245	0	0	_aMacrocyclic prolinyl acyl guanidines as inhibitors of β-secretase (BACE). _h[electronic resource]
260			_bBioorganic & medicinal chemistry letters _cNov 2015
300			_a5040-7 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aATP Binding Cassette Transporter, Subfamily B, Member 1 _xmetabolism
650	0	4	_aAmyloid Precursor Protein Secretases _xantagonists & inhibitors
650	0	4	_aAmyloid beta-Peptides _xbiosynthesis
650	0	4	_aAnimals
650	0	4	_aAspartic Acid Endopeptidases _xantagonists & inhibitors
650	0	4	_aCaco-2 Cells
650	0	4	_aCathepsin D _xantagonists & inhibitors
650	0	4	_aCathepsin E _xantagonists & inhibitors
650	0	4	_aDogs
650	0	4	_aGuanidines _xchemical synthesis
650	0	4	_aHumans
650	0	4	_aMacrocyclic Compounds _xchemical synthesis
650	0	4	_aMadin Darby Canine Kidney Cells
650	0	4	_aMale
650	0	4	_aMice
650	0	4	_aMolecular Docking Simulation
650	0	4	_aPepsin A _xantagonists & inhibitors
650	0	4	_aProline _xanalogs & derivatives
650	0	4	_aProtease Inhibitors _xchemical synthesis
700	1		_aGuernon, Jason M
700	1		_aWu, Yong-Jin
700	1		_aZhang, Yunhui
700	1		_aShi, Joe
700	1		_aZhai, Weixu
700	1		_aZhu, Shirong
700	1		_aGerritz, Samuel W
700	1		_aToyn, Jeremy H
700	1		_aMeredith, Jere E
700	1		_aBarten, Donna M
700	1		_aBurton, Catherine R
700	1		_aAlbright, Charles F
700	1		_aGood, Andrew C
700	1		_aGrace, James E
700	1		_aLentz, Kimberley A
700	1		_aOlson, Richard E
700	1		_aMacor, John E
700	1		_aThompson, Lorin A
773	0		_tBioorganic & medicinal chemistry letters _gvol. 25 _gno. 22 _gp. 5040-7
856	4	0	_uhttps://doi.org/10.1016/j.bmcl.2015.10.031 _zAvailable from publisher's website
999			_c25383388 _d25383388