000 01674 a2200457 4500
005 20250517060409.0
264 0 _c20160926
008 201609s 0 0 eng d
022 _a1873-1708
024 7 _a10.1016/j.reprotox.2015.10.008
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aClarke, D O
245 0 0 _aAssessment of ixekizumab, an interleukin-17A monoclonal antibody, for potential effects on reproduction and development, including immune system function, in cynomolgus monkeys.
_h[electronic resource]
260 _bReproductive toxicology (Elmsford, N.Y.)
_cDec 2015
300 _a160-73 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAge Factors
650 0 4 _aAnimals
650 0 4 _aAntibodies, Monoclonal, Humanized
_xtoxicity
650 0 4 _aBiomarkers
_xblood
650 0 4 _aEmbryonic Development
_xdrug effects
650 0 4 _aFemale
650 0 4 _aFertility
_xdrug effects
650 0 4 _aFetal Development
_xdrug effects
650 0 4 _aFetus
_xdrug effects
650 0 4 _aGestational Age
650 0 4 _aImmune System
_xdrug effects
650 0 4 _aImmunologic Factors
_xtoxicity
650 0 4 _aMacaca fascicularis
650 0 4 _aMale
650 0 4 _aPregnancy
650 0 4 _aPrenatal Exposure Delayed Effects
650 0 4 _aReproduction
_xdrug effects
650 0 4 _aRisk Assessment
700 1 _aHilbish, K G
700 1 _aWaters, D G
700 1 _aNewcomb, D L
700 1 _aChellman, G J
773 0 _tReproductive toxicology (Elmsford, N.Y.)
_gvol. 58
_gp. 160-73
856 4 0 _uhttps://doi.org/10.1016/j.reprotox.2015.10.008
_zAvailable from publisher's website
999 _c25369245
_d25369245