| 000 | 01463 a2200397 4500 | ||
|---|---|---|---|
| 005 | 20250517060147.0 | ||
| 264 | 0 | _c20160811 | |
| 008 | 201608s 0 0 eng d | ||
| 022 | _a1464-3405 | ||
| 024 | 7 |
_a10.1016/j.bmcl.2015.10.013 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aGarcia-Barrantes, Pedro M | |
| 245 | 0 | 0 |
_aLead optimization of the VU0486321 series of mGlu1 PAMs. Part 1: SAR of modifications to the central aryl core. _h[electronic resource] |
| 260 |
_bBioorganic & medicinal chemistry letters _cNov 2015 |
||
| 300 |
_a5107-10 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAllosteric Regulation |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aBrain _xmetabolism |
| 650 | 0 | 4 |
_aCoumarins _xblood |
| 650 | 0 | 4 |
_aFurans _xblood |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aMicrosomes, Liver _xmetabolism |
| 650 | 0 | 4 |
_aPhthalimides _xblood |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 |
_aReceptors, Metabotropic Glutamate _xagonists |
| 650 | 0 | 4 | _aStereoisomerism |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 700 | 1 | _aCho, Hyekyung P | |
| 700 | 1 | _aBlobaum, Anna L | |
| 700 | 1 | _aNiswender, Colleen M | |
| 700 | 1 | _aConn, P Jeffrey | |
| 700 | 1 | _aLindsley, Craig W | |
| 773 | 0 |
_tBioorganic & medicinal chemistry letters _gvol. 25 _gno. 22 _gp. 5107-10 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bmcl.2015.10.013 _zAvailable from publisher's website |
| 999 |
_c25363732 _d25363732 |
||