000 02100 a2200613 4500
005 20250517055853.0
264 0 _c20160829
008 201608s 0 0 eng d
022 _a1551-4005
024 7 _a10.1080/15384101.2015.1090065
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aJain, Rajul K
245 0 0 _aNovel phase I study combining G1 phase, S phase, and G2/M phase cell cycle inhibitors in patients with advanced malignancies.
_h[electronic resource]
260 _bCell cycle (Georgetown, Tex.)
_c2015
300 _a3434-40 p.
_bdigital
500 _aPublication Type: Clinical Trial, Phase I; Journal Article
650 0 4 _aAdolescent
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAged, 80 and over
650 0 4 _aAntineoplastic Combined Chemotherapy Protocols
_xadverse effects
650 0 4 _aBortezomib
_xadministration & dosage
650 0 4 _aComputer Simulation
650 0 4 _aDisease Progression
650 0 4 _aDisease-Free Survival
650 0 4 _aDrug Administration Schedule
650 0 4 _aFemale
650 0 4 _aG1 Phase Cell Cycle Checkpoints
_xdrug effects
650 0 4 _aG2 Phase Cell Cycle Checkpoints
_xdrug effects
650 0 4 _aHumans
650 0 4 _aKaplan-Meier Estimate
650 0 4 _aMale
650 0 4 _aMaximum Tolerated Dose
650 0 4 _aMiddle Aged
650 0 4 _aModels, Biological
650 0 4 _aMolecular Targeted Therapy
650 0 4 _aNeoplasms
_xdrug therapy
650 0 4 _aS Phase Cell Cycle Checkpoints
_xdrug effects
650 0 4 _aSirolimus
_xadministration & dosage
650 0 4 _aTexas
650 0 4 _aTime Factors
650 0 4 _aTopotecan
_xadministration & dosage
650 0 4 _aTreatment Outcome
650 0 4 _aYoung Adult
700 1 _aHong, David S
700 1 _aNaing, Aung
700 1 _aWheler, Jennifer
700 1 _aHelgason, Thorunn
700 1 _aShi, Nai-Yi
700 1 _aGad, Yash
700 1 _aKurzrock, Razelle
773 0 _tCell cycle (Georgetown, Tex.)
_gvol. 14
_gno. 21
_gp. 3434-40
856 4 0 _uhttps://doi.org/10.1080/15384101.2015.1090065
_zAvailable from publisher's website
999 _c25354550
_d25354550