000 01883 a2200529 4500
005 20250517054556.0
264 0 _c20170327
008 201703s 0 0 eng d
022 _a1860-7187
024 7 _a10.1002/cmdc.201500383
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBenek, Ondrej
245 0 0 _aDesign, Synthesis and in vitro Evaluation of Indolotacrine Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease.
_h[electronic resource]
260 _bChemMedChem
_c06 2016
300 _a1264-9 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAcetylcholinesterase
_xchemistry
650 0 4 _aAlzheimer Disease
_xdrug therapy
650 0 4 _aBlood-Brain Barrier
_xmetabolism
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aCholinesterase Inhibitors
_xchemical synthesis
650 0 4 _aDrug Design
650 0 4 _aHep G2 Cells
650 0 4 _aHumans
650 0 4 _aIndoles
_xchemical synthesis
650 0 4 _aInhibitory Concentration 50
650 0 4 _aLigands
650 0 4 _aMonoamine Oxidase
_xchemistry
650 0 4 _aMonoamine Oxidase Inhibitors
_xchemical synthesis
650 0 4 _aQuinolines
_xchemical synthesis
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTacrine
_xchemistry
700 1 _aSoukup, Ondrej
700 1 _aPasdiorova, Marketa
700 1 _aHroch, Lukas
700 1 _aSepsova, Vendula
700 1 _aJost, Petr
700 1 _aHrabinova, Martina
700 1 _aJun, Daniel
700 1 _aKuca, Kamil
700 1 _aZala, Dominykas
700 1 _aRamsay, Rona R
700 1 _aMarco-Contelles, José
700 1 _aMusilek, Kamil
773 0 _tChemMedChem
_gvol. 11
_gno. 12
_gp. 1264-9
856 4 0 _uhttps://doi.org/10.1002/cmdc.201500383
_zAvailable from publisher's website
999 _c25316155
_d25316155