000 01900 a2200553 4500
005 20250517054052.0
264 0 _c20160510
008 201605s 0 0 eng d
022 _a1860-7187
024 7 _a10.1002/cmdc.201500334
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSemenov, Vyacheslav E
245 0 0 _a6-Methyluracil Derivatives as Bifunctional Acetylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease.
_h[electronic resource]
260 _bChemMedChem
_cNov 2015
300 _a1863-74 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAcetylcholinesterase
_xmetabolism
650 0 4 _aAlzheimer Disease
_xdrug therapy
650 0 4 _aAnimals
650 0 4 _aBehavior, Animal
_xdrug effects
650 0 4 _aBrain
_xenzymology
650 0 4 _aCholinesterase Inhibitors
_xchemical synthesis
650 0 4 _aCrystallography, X-Ray
650 0 4 _aDisease Models, Animal
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aHumans
650 0 4 _aMice
650 0 4 _aMice, Transgenic
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Structure
650 0 4 _aStructure-Activity Relationship
650 0 4 _aUracil
_xanalogs & derivatives
700 1 _aZueva, Irina V
700 1 _aMukhamedyarov, Marat A
700 1 _aLushchekina, Sofya V
700 1 _aKharlamova, Alexandra D
700 1 _aPetukhova, Elena O
700 1 _aMikhailov, Anatoly S
700 1 _aPodyachev, Sergey N
700 1 _aSaifina, Lilya F
700 1 _aPetrov, Konstantin A
700 1 _aMinnekhanova, Oksana A
700 1 _aZobov, Vladimir V
700 1 _aNikolsky, Evgeny E
700 1 _aMasson, Patrick
700 1 _aReznik, Vladimir S
773 0 _tChemMedChem
_gvol. 10
_gno. 11
_gp. 1863-74
856 4 0 _uhttps://doi.org/10.1002/cmdc.201500334
_zAvailable from publisher's website
999 _c25301867
_d25301867