| 000 | 02296 a2200745 4500 | ||
|---|---|---|---|
| 005 | 20250517053615.0 | ||
| 264 | 0 | _c20160202 | |
| 008 | 201602s 0 0 eng d | ||
| 022 | _a1520-4804 | ||
| 024 | 7 |
_a10.1021/acs.jmedchem.5b01037 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aRaheem, Izzat T | |
| 245 | 0 | 0 |
_aDiscovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cOct 2015 |
||
| 300 |
_a8154-65 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 | _aArea Under Curve |
| 650 | 0 | 4 | _aDogs |
| 650 | 0 | 4 | _aDose-Response Relationship, Drug |
| 650 | 0 | 4 | _aDrug Design |
| 650 | 0 | 4 |
_aHIV Integrase _xdrug effects |
| 650 | 0 | 4 |
_aHIV Integrase Inhibitors _xchemical synthesis |
| 650 | 0 | 4 |
_aHIV-1 _xdrug effects |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 | _aProdrugs |
| 650 | 0 | 4 |
_aPyridones _xchemical synthesis |
| 650 | 0 | 4 | _aRats |
| 700 | 1 | _aWalji, Abbas M | |
| 700 | 1 | _aKlein, Daniel | |
| 700 | 1 | _aSanders, John M | |
| 700 | 1 | _aPowell, David A | |
| 700 | 1 | _aAbeywickrema, Pravien | |
| 700 | 1 | _aBarbe, Guillaume | |
| 700 | 1 | _aBennet, Amrith | |
| 700 | 1 | _aChilders, Karla | |
| 700 | 1 | _aChristensen, Melodie | |
| 700 | 1 | _aClas, Sophie Dorothee | |
| 700 | 1 | _aDubost, David | |
| 700 | 1 | _aEmbrey, Mark | |
| 700 | 1 | _aGrobler, Jay | |
| 700 | 1 | _aHafey, Michael J | |
| 700 | 1 | _aHartingh, Timothy J | |
| 700 | 1 | _aHazuda, Daria J | |
| 700 | 1 | _aKuethe, Jeffrey T | |
| 700 | 1 | _aMcCabe Dunn, Jamie | |
| 700 | 1 | _aMiller, Michael D | |
| 700 | 1 | _aMoore, Keith P | |
| 700 | 1 | _aNolting, Andrew | |
| 700 | 1 | _aPajkovic, Natasa | |
| 700 | 1 | _aPatel, Sangita | |
| 700 | 1 | _aPeng, Zuihui | |
| 700 | 1 | _aRada, Vanessa | |
| 700 | 1 | _aRearden, Paul | |
| 700 | 1 | _aSchreier, John D | |
| 700 | 1 | _aSisko, John | |
| 700 | 1 | _aSteele, Thomas G | |
| 700 | 1 | _aTruchon, Jean-François | |
| 700 | 1 | _aWai, John | |
| 700 | 1 | _aXu, Min | |
| 700 | 1 | _aColeman, Paul J | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 58 _gno. 20 _gp. 8154-65 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/acs.jmedchem.5b01037 _zAvailable from publisher's website |
| 999 |
_c25287517 _d25287517 |
||