000 02188 a2200601 4500
005 20250517052403.0
264 0 _c20160209
008 201602s 0 0 eng d
022 _a1538-7445
024 7 _a10.1158/0008-5472.CAN-15-0509
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSingleton, Katherine R
245 0 0 _aKinome RNAi Screens Reveal Synergistic Targeting of MTOR and FGFR1 Pathways for Treatment of Lung Cancer and HNSCC.
_h[electronic resource]
260 _bCancer research
_cOct 2015
300 _a4398-406 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aBenzamides
_xpharmacology
650 0 4 _aCarcinoma, Non-Small-Cell Lung
_xdrug therapy
650 0 4 _aCell Line, Tumor
650 0 4 _aDisease Models, Animal
650 0 4 _aDrug Resistance, Neoplasm
650 0 4 _aDrug Synergism
650 0 4 _aGene Library
650 0 4 _aGenes, Essential
650 0 4 _aGenomics
_xmethods
650 0 4 _aHumans
650 0 4 _aLung Neoplasms
_xdrug therapy
650 0 4 _aMorpholines
_xpharmacology
650 0 4 _aPiperazines
_xpharmacology
650 0 4 _aProtein Binding
650 0 4 _aProtein Kinase Inhibitors
_xpharmacology
650 0 4 _aPyrazoles
_xpharmacology
650 0 4 _aPyrimidines
650 0 4 _aRNA Interference
650 0 4 _aRNA, Small Interfering
_xgenetics
650 0 4 _aReceptor, Fibroblast Growth Factor, Type 1
_xantagonists & inhibitors
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aTOR Serine-Threonine Kinases
_xantagonists & inhibitors
650 0 4 _aTumor Burden
_xdrug effects
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aHinz, Trista K
700 1 _aKleczko, Emily K
700 1 _aMarek, Lindsay A
700 1 _aKwak, Jeff
700 1 _aHarp, Taylor
700 1 _aKim, Jihye
700 1 _aTan, Aik Choon
700 1 _aHeasley, Lynn E
773 0 _tCancer research
_gvol. 75
_gno. 20
_gp. 4398-406
856 4 0 _uhttps://doi.org/10.1158/0008-5472.CAN-15-0509
_zAvailable from publisher's website
999 _c25251025
_d25251025