000 01518 a2200409 4500
005 20250517052049.0
264 0 _c20160720
008 201607s 0 0 eng d
022 _a1881-1469
024 7 _a10.1038/ja.2015.94
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKakeya, Hideaki
245 0 0 _aRQN-18690A (18-deoxyherboxidiene) targets SF3b, a spliceosome component, and inhibits angiogenesis.
_h[electronic resource]
260 _bThe Journal of antibiotics
_cFeb 2016
300 _a121-3 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aCells, Cultured
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aFatty Alcohols
_xpharmacology
650 0 4 _aHuman Umbilical Vein Endothelial Cells
_xdrug effects
650 0 4 _aHumans
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Structure
650 0 4 _aNeovascularization, Physiologic
_xdrug effects
650 0 4 _aPhosphoproteins
_xantagonists & inhibitors
650 0 4 _aPyrans
_xpharmacology
650 0 4 _aRNA Splicing Factors
650 0 4 _aRibonucleoprotein, U2 Small Nuclear
_xantagonists & inhibitors
650 0 4 _aSpliceosomes
_xdrug effects
700 1 _aKaida, Daisuke
700 1 _aSekiya, Hiromi
700 1 _aNagai, Koji
700 1 _aYoshida, Minoru
700 1 _aOsada, Hiroyuki
773 0 _tThe Journal of antibiotics
_gvol. 69
_gno. 2
_gp. 121-3
856 4 0 _uhttps://doi.org/10.1038/ja.2015.94
_zAvailable from publisher's website
999 _c25242632
_d25242632