000 02242 a2200589 4500
005 20250517051737.0
264 0 _c20161107
008 201611s 0 0 eng d
022 _a1366-5928
024 7 _a10.3109/00498254.2015.1081993
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aReese, Melinda J
245 0 0 _aDrug interaction profile of the HIV integrase inhibitor cabotegravir: assessment from in vitro studies and a clinical investigation with midazolam.
_h[electronic resource]
260 _bXenobiotica; the fate of foreign compounds in biological systems
_c2016
300 _a445-56 p.
_bdigital
500 _aPublication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aATP-Binding Cassette Transporters
_xmetabolism
650 0 4 _aAdministration, Oral
650 0 4 _aAdolescent
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAnimals
650 0 4 _aAnti-HIV Agents
_xadministration & dosage
650 0 4 _aArea Under Curve
650 0 4 _aCytochrome P-450 CYP3A
_xchemistry
650 0 4 _aDogs
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Interactions
650 0 4 _aFemale
650 0 4 _aHIV Infections
_xdrug therapy
650 0 4 _aHIV Integrase Inhibitors
_xchemistry
650 0 4 _aHepatocytes
_xdrug effects
650 0 4 _aHumans
650 0 4 _aInhibitory Concentration 50
650 0 4 _aMadin Darby Canine Kidney Cells
650 0 4 _aMale
650 0 4 _aMidazolam
_xadministration & dosage
650 0 4 _aMiddle Aged
650 0 4 _aOrganic Anion Transport Protein 1
_xantagonists & inhibitors
650 0 4 _aOrganic Anion Transporters
_xmetabolism
650 0 4 _aOrganic Anion Transporters, Sodium-Independent
_xantagonists & inhibitors
650 0 4 _aPyridones
_xadministration & dosage
650 0 4 _aYoung Adult
700 1 _aBowers, Gary D
700 1 _aHumphreys, Joan E
700 1 _aGould, Elizabeth P
700 1 _aFord, Susan L
700 1 _aWebster, Lindsey O
700 1 _aPolli, Joseph W
773 0 _tXenobiotica; the fate of foreign compounds in biological systems
_gvol. 46
_gno. 5
_gp. 445-56
856 4 0 _uhttps://doi.org/10.3109/00498254.2015.1081993
_zAvailable from publisher's website
999 _c25232597
_d25232597