000 01850 a2200517 4500
005 20250517051433.0
264 0 _c20160104
008 201601s 0 0 eng d
022 _a1521-0103
024 7 _a10.1124/jpet.115.226969
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aPandey, Sanjay K
245 0 0 _aIdentification and characterization of modified antisense oligonucleotides targeting DMPK in mice and nonhuman primates for the treatment of myotonic dystrophy type 1.
_h[electronic resource]
260 _bThe Journal of pharmacology and experimental therapeutics
_cNov 2015
300 _a329-40 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural
650 0 4 _aAnimals
650 0 4 _aCell Line
650 0 4 _aHumans
650 0 4 _aMacaca fascicularis
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Transgenic
650 0 4 _aMuscle, Skeletal
_xenzymology
650 0 4 _aMyotonic Dystrophy
_xdrug therapy
650 0 4 _aMyotonin-Protein Kinase
_xantagonists & inhibitors
650 0 4 _aOligonucleotides
_xchemistry
650 0 4 _aOligonucleotides, Antisense
_xpharmacology
650 0 4 _aRNA, Messenger
_xmetabolism
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
700 1 _aWheeler, Thurman M
700 1 _aJustice, Samantha L
700 1 _aKim, Aneeza
700 1 _aYounis, Husam S
700 1 _aGattis, Danielle
700 1 _aJauvin, Dominic
700 1 _aPuymirat, Jack
700 1 _aSwayze, Eric E
700 1 _aFreier, Susan M
700 1 _aBennett, C Frank
700 1 _aThornton, Charles A
700 1 _aMacLeod, A Robert
773 0 _tThe Journal of pharmacology and experimental therapeutics
_gvol. 355
_gno. 2
_gp. 329-40
856 4 0 _uhttps://doi.org/10.1124/jpet.115.226969
_zAvailable from publisher's website
999 _c25223109
_d25223109