000 | 01821 a2200481 4500 | ||
---|---|---|---|
005 | 20250517051429.0 | ||
264 | 0 | _c20160801 | |
008 | 201608s 0 0 eng d | ||
022 | _a1573-6768 | ||
024 | 7 |
_a10.1007/s10522-015-9605-9 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aSong, Tuzz-Ying | |
245 | 0 | 0 |
_aA Nampt inhibitor FK866 mimics vitamin B3 deficiency by causing senescence of human fibroblastic Hs68 cells via attenuation of NAD(+)-SIRT1 signaling. _h[electronic resource] |
260 |
_bBiogerontology _cDec 2015 |
||
300 |
_a789-800 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 |
_aAMP-Activated Protein Kinases _xmetabolism |
650 | 0 | 4 |
_aAcrylamides _xpharmacology |
650 | 0 | 4 | _aCell Line |
650 | 0 | 4 |
_aCell Proliferation _xdrug effects |
650 | 0 | 4 |
_aCellular Senescence _xdrug effects |
650 | 0 | 4 |
_aCytokines _xantagonists & inhibitors |
650 | 0 | 4 |
_aEnzyme Inhibitors _xpharmacology |
650 | 0 | 4 |
_aFibroblasts _xcytology |
650 | 0 | 4 |
_aGlutathione _xmetabolism |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aNAD _xmetabolism |
650 | 0 | 4 |
_aNADP _xmetabolism |
650 | 0 | 4 |
_aNiacin _xpharmacology |
650 | 0 | 4 |
_aNiacinamide _xdeficiency |
650 | 0 | 4 |
_aNicotinamide Phosphoribosyltransferase _xantagonists & inhibitors |
650 | 0 | 4 |
_aPiperidines _xpharmacology |
650 | 0 | 4 |
_aSignal Transduction _xdrug effects |
650 | 0 | 4 |
_aSirtuin 1 _xmetabolism |
650 | 0 | 4 |
_aTOR Serine-Threonine Kinases _xmetabolism |
650 | 0 | 4 |
_aTumor Suppressor Protein p53 _xmetabolism |
700 | 1 | _aYeh, Shu-Lan | |
700 | 1 | _aHu, Miao-Lin | |
700 | 1 | _aChen, Mei-Yau | |
700 | 1 | _aYang, Nae-Cherng | |
773 | 0 |
_tBiogerontology _gvol. 16 _gno. 6 _gp. 789-800 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1007/s10522-015-9605-9 _zAvailable from publisher's website |
999 |
_c25222876 _d25222876 |