| 000 | 01767 a2200481 4500 | ||
|---|---|---|---|
| 005 | 20250517050848.0 | ||
| 264 | 0 | _c20160614 | |
| 008 | 201606s 0 0 eng d | ||
| 022 | _a1768-3254 | ||
| 024 | 7 |
_a10.1016/j.ejmech.2015.08.032 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aMajumdar, Papiya | |
| 245 | 0 | 0 |
_aDesign, synthesis and evaluation of thiohydantoin derivatives as potent topoisomerase I (Top1) inhibitors with anticancer activity. _h[electronic resource] |
| 260 |
_bEuropean journal of medicinal chemistry _cSep 2015 |
||
| 300 |
_a540-51 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 |
_aAntineoplastic Agents _xchemical synthesis |
| 650 | 0 | 4 |
_aCell Proliferation _xdrug effects |
| 650 | 0 | 4 |
_aCell Survival _xdrug effects |
| 650 | 0 | 4 |
_aDNA Topoisomerases, Type I _xmetabolism |
| 650 | 0 | 4 | _aDose-Response Relationship, Drug |
| 650 | 0 | 4 | _aDrug Design |
| 650 | 0 | 4 | _aDrug Screening Assays, Antitumor |
| 650 | 0 | 4 | _aHEK293 Cells |
| 650 | 0 | 4 | _aHeLa Cells |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMCF-7 Cells |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 | _aMolecular Structure |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 650 | 0 | 4 |
_aThiohydantoins _xchemical synthesis |
| 650 | 0 | 4 |
_aTopoisomerase I Inhibitors _xchemical synthesis |
| 700 | 1 | _aBathula, Chandramohan | |
| 700 | 1 | _aBasu, Suparna M | |
| 700 | 1 | _aDas, Subhendu K | |
| 700 | 1 | _aAgarwal, Rahul | |
| 700 | 1 | _aHati, Santanu | |
| 700 | 1 | _aSingh, Ashutosh | |
| 700 | 1 | _aSen, Subhabrata | |
| 700 | 1 | _aDas, Benu Brata | |
| 773 | 0 |
_tEuropean journal of medicinal chemistry _gvol. 102 _gp. 540-51 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.ejmech.2015.08.032 _zAvailable from publisher's website |
| 999 |
_c25206883 _d25206883 |
||