000 02084 a2200541 4500
005 20250517045959.0
264 0 _c20160815
008 201608s 0 0 eng d
022 _a2352-3964
024 7 _a10.1016/j.ebiom.2015.04.005
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aUckun, Fatih M
245 0 0 _aLiposomal Nanoparticles of a Spleen Tyrosine Kinase P-Site Inhibitor Amplify the Potency of Low Dose Total Body Irradiation Against Aggressive B-Precursor Leukemia and Yield Superior Survival Outcomes in Mice.
_h[electronic resource]
260 _bEBioMedicine
_cJun 2015
300 _a554-62 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural
650 0 4 _aAnimals
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBone Marrow Transplantation
650 0 4 _aCell Line, Tumor
650 0 4 _aCombined Modality Therapy
_xmethods
650 0 4 _aDisease-Free Survival
650 0 4 _aFusion Proteins, bcr-abl
_xgenetics
650 0 4 _aGene Expression
_xdrug effects
650 0 4 _aHumans
650 0 4 _aIntracellular Signaling Peptides and Proteins
_xantagonists & inhibitors
650 0 4 _aLiposomes
_xtherapeutic use
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMice, Inbred NOD
650 0 4 _aMice, SCID
650 0 4 _aMice, Transgenic
650 0 4 _aNanoparticles
650 0 4 _aPrecursor B-Cell Lymphoblastic Leukemia-Lymphoma
_xmortality
650 0 4 _aProtein Kinase Inhibitors
_xtherapeutic use
650 0 4 _aProtein-Tyrosine Kinases
_xantagonists & inhibitors
650 0 4 _aRadiation Tolerance
_xdrug effects
650 0 4 _aRadiation-Sensitizing Agents
_xtherapeutic use
650 0 4 _aSyk Kinase
650 0 4 _aTreatment Outcome
650 0 4 _aWhole-Body Irradiation
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aMyers, Dorothea E
700 1 _aCheng, Jianjun
700 1 _aQazi, Sanjive
773 0 _tEBioMedicine
_gvol. 2
_gno. 6
_gp. 554-62
856 4 0 _uhttps://doi.org/10.1016/j.ebiom.2015.04.005
_zAvailable from publisher's website
999 _c25181246
_d25181246