000 | 02493 a2200769 4500 | ||
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005 | 20250517045639.0 | ||
264 | 0 | _c20151214 | |
008 | 201512s 0 0 eng d | ||
022 | _a1520-4804 | ||
024 | 7 |
_a10.1021/acs.jmedchem.5b01082 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aEngel, Julian | |
245 | 0 | 0 |
_aTargeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach. _h[electronic resource] |
260 |
_bJournal of medicinal chemistry _cSep 2015 |
||
300 |
_a6844-63 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 |
_aAntineoplastic Agents _xchemistry |
650 | 0 | 4 | _aCarcinoma, Non-Small-Cell Lung |
650 | 0 | 4 | _aCell Line, Tumor |
650 | 0 | 4 | _aCell Membrane Permeability |
650 | 0 | 4 | _aCrystallography, X-Ray |
650 | 0 | 4 | _aDatabases, Chemical |
650 | 0 | 4 | _aDrug Design |
650 | 0 | 4 | _aDrug Resistance, Neoplasm |
650 | 0 | 4 |
_aErbB Receptors _xantagonists & inhibitors |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aKinetics |
650 | 0 | 4 | _aLung Neoplasms |
650 | 0 | 4 | _aModels, Molecular |
650 | 0 | 4 | _aMolecular Conformation |
650 | 0 | 4 | _aMutation |
650 | 0 | 4 |
_aPyrazoles _xchemistry |
650 | 0 | 4 |
_aPyrimidines _xchemistry |
650 | 0 | 4 |
_aQuinazolines _xchemistry |
650 | 0 | 4 | _aSmall Molecule Libraries |
650 | 0 | 4 | _aSolubility |
650 | 0 | 4 | _aStructure-Activity Relationship |
650 | 0 | 4 |
_asrc-Family Kinases _xchemistry |
700 | 1 | _aRichters, André | |
700 | 1 | _aGetlik, Matthäus | |
700 | 1 | _aTomassi, Stefano | |
700 | 1 | _aKeul, Marina | |
700 | 1 | _aTermathe, Martin | |
700 | 1 | _aLategahn, Jonas | |
700 | 1 | _aBecker, Christian | |
700 | 1 | _aMayer-Wrangowski, Svenja | |
700 | 1 | _aGrütter, Christian | |
700 | 1 | _aUhlenbrock, Niklas | |
700 | 1 | _aKrüll, Jasmin | |
700 | 1 | _aSchaumann, Niklas | |
700 | 1 | _aEppmann, Simone | |
700 | 1 | _aKibies, Patrick | |
700 | 1 | _aHoffgaard, Franziska | |
700 | 1 | _aHeil, Jochen | |
700 | 1 | _aMenninger, Sascha | |
700 | 1 | _aOrtiz-Cuaran, Sandra | |
700 | 1 | _aHeuckmann, Johannes M | |
700 | 1 | _aTinnefeld, Verena | |
700 | 1 | _aZahedi, René P | |
700 | 1 | _aSos, Martin L | |
700 | 1 | _aSchultz-Fademrecht, Carsten | |
700 | 1 | _aThomas, Roman K | |
700 | 1 | _aKast, Stefan M | |
700 | 1 | _aRauh, Daniel | |
773 | 0 |
_tJournal of medicinal chemistry _gvol. 58 _gno. 17 _gp. 6844-63 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1021/acs.jmedchem.5b01082 _zAvailable from publisher's website |
999 |
_c25170804 _d25170804 |