000 01477 a2200409 4500
005 20250517045346.0
264 0 _c20160718
008 201607s 0 0 eng d
022 _a1521-009X
024 7 _a10.1124/dmd.115.065656
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aScheer, Nico
245 0 0 _aDefining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model.
_h[electronic resource]
260 _bDrug metabolism and disposition: the biological fate of chemicals
_cNov 2015
300 _a1679-90 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aCytochrome P-450 CYP3A
_xgenetics
650 0 4 _aHumans
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Transgenic
650 0 4 _aMicrosomes, Liver
_xdrug effects
650 0 4 _aModels, Animal
650 0 4 _aPharmaceutical Preparations
_xadministration & dosage
650 0 4 _aSignal Transduction
_xdrug effects
700 1 _aKapelyukh, Yury
700 1 _aRode, Anja
700 1 _aOswald, Stefan
700 1 _aBusch, Diana
700 1 _aMcLaughlin, Lesley A
700 1 _aLin, De
700 1 _aHenderson, Colin J
700 1 _aWolf, C Roland
773 0 _tDrug metabolism and disposition: the biological fate of chemicals
_gvol. 43
_gno. 11
_gp. 1679-90
856 4 0 _uhttps://doi.org/10.1124/dmd.115.065656
_zAvailable from publisher's website
999 _c25161939
_d25161939