000			01631 a2200433 4500
005			20250517045336.0
264		0	_c20160601
008			201606s 0 0 eng d
022			_a1476-5551
024	7		_a10.1038/leu.2015.222 _2doi
040			_aNLM _beng _cNLM
100	1		_aAkahane, K
245	0	0	_aHSP90 inhibition leads to degradation of the TYK2 kinase and apoptotic cell death in T-cell acute lymphoblastic leukemia. _h[electronic resource]
260			_bLeukemia _cJan 2016
300			_a219-28 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650	0	4	_aApoptosis _xdrug effects
650	0	4	_aApoptosis Regulatory Proteins _xanalysis
650	0	4	_aBcl-2-Like Protein 11
650	0	4	_aCell Line, Tumor
650	0	4	_aHSP90 Heat-Shock Proteins _xantagonists & inhibitors
650	0	4	_aHumans
650	0	4	_aIsoxazoles _xtherapeutic use
650	0	4	_aMembrane Proteins _xanalysis
650	0	4	_aPrecursor T-Cell Lymphoblastic Leukemia-Lymphoma _xdrug therapy
650	0	4	_aProto-Oncogene Proteins _xanalysis
650	0	4	_aProto-Oncogene Proteins c-bcl-2 _xanalysis
650	0	4	_aResorcinols _xtherapeutic use
650	0	4	_aTYK2 Kinase _xmetabolism
650	0	4	_abcl-Associated Death Protein _xanalysis
700	1		_aSanda, T
700	1		_aMansour, M R
700	1		_aRadimerski, T
700	1		_aDeAngelo, D J
700	1		_aWeinstock, D M
700	1		_aLook, A T
773	0		_tLeukemia _gvol. 30 _gno. 1 _gp. 219-28
856	4	0	_uhttps://doi.org/10.1038/leu.2015.222 _zAvailable from publisher's website
999			_c25161404 _d25161404