000 01811 a2200469 4500
005 20250517045043.0
264 0 _c20160407
008 201604s 0 0 eng d
022 _a1177-8881
024 7 _a10.2147/DDDT.S86725
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aChoi, YoonJung
245 0 0 _aComparison of the pharmacokinetics and tolerability of HCP1004 (a fixed-dose combination of naproxen and esomeprazole strontium) and VIMOVO® (a marketed fixed-dose combination of naproxen and esomeprazole magnesium) in healthy volunteers.
_h[electronic resource]
260 _bDrug design, development and therapy
_c2015
300 _a4127-35 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
650 0 4 _aAdministration, Oral
650 0 4 _aAdult
650 0 4 _aAnti-Inflammatory Agents, Non-Steroidal
_xadministration & dosage
650 0 4 _aArea Under Curve
650 0 4 _aChemistry, Pharmaceutical
650 0 4 _aCross-Over Studies
650 0 4 _aDrug Combinations
650 0 4 _aEsomeprazole
_xadministration & dosage
650 0 4 _aHalf-Life
650 0 4 _aHealthy Volunteers
650 0 4 _aHumans
650 0 4 _aMale
650 0 4 _aMetabolic Clearance Rate
650 0 4 _aMiddle Aged
650 0 4 _aModels, Biological
650 0 4 _aNaproxen
_xadministration & dosage
650 0 4 _aProton Pump Inhibitors
_xadministration & dosage
650 0 4 _aRepublic of Korea
650 0 4 _aYoung Adult
700 1 _aHan, HyeKyung
700 1 _aShin, Dongseong
700 1 _aLim, Kyoung Soo
700 1 _aYu, Kyung-Sang
773 0 _tDrug design, development and therapy
_gvol. 9
_gp. 4127-35
856 4 0 _uhttps://doi.org/10.2147/DDDT.S86725
_zAvailable from publisher's website
999 _c25153964
_d25153964