000 02010 a2200589 4500
005 20250517044737.0
264 0 _c20160506
008 201605s 0 0 eng d
022 _a1932-6203
024 7 _a10.1371/journal.pone.0135083
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aChoi, Yong-Min
245 0 0 _aMechanism of Cisplatin-Induced Cytotoxicity Is Correlated to Impaired Metabolism Due to Mitochondrial ROS Generation.
_h[electronic resource]
260 _bPloS one
_c2015
300 _ae0135083 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAcetylcysteine
_xpharmacology
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xtoxicity
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aCell Line
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCisplatin
_xtoxicity
650 0 4 _aCitric Acid Cycle
_xdrug effects
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aEpithelial Cells
_xcytology
650 0 4 _aGene Expression Regulation
650 0 4 _aGlycolysis
_xdrug effects
650 0 4 _aHumans
650 0 4 _aInjections, Intraperitoneal
650 0 4 _aKidney Tubules
_xcytology
650 0 4 _aL-Lactate Dehydrogenase
_xgenetics
650 0 4 _aMale
650 0 4 _aMembrane Potential, Mitochondrial
_xdrug effects
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aReactive Oxygen Species
_xagonists
650 0 4 _aTumor Suppressor Protein p53
_xagonists
700 1 _aKim, Han-Kyul
700 1 _aShim, Wooyoung
700 1 _aAnwar, Muhammad Ayaz
700 1 _aKwon, Ji-Woong
700 1 _aKwon, Hyuk-Kwon
700 1 _aKim, Hyung Joong
700 1 _aJeong, Hyobin
700 1 _aKim, Hwan Myung
700 1 _aHwang, Daehee
700 1 _aKim, Hyung Sik
700 1 _aChoi, Sangdun
773 0 _tPloS one
_gvol. 10
_gno. 8
_gp. e0135083
856 4 0 _uhttps://doi.org/10.1371/journal.pone.0135083
_zAvailable from publisher's website
999 _c25144273
_d25144273