| 000 | 01805 a2200493 4500 | ||
|---|---|---|---|
| 005 | 20250517044343.0 | ||
| 264 | 0 | _c20170829 | |
| 008 | 201708s 0 0 eng d | ||
| 022 | _a2045-2322 | ||
| 024 | 7 |
_a10.1038/srep12728 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aSonamoto, Rie | |
| 245 | 0 | 0 |
_aIdentification of a DYRK1A Inhibitor that Induces Degradation of the Target Kinase using Co-chaperone CDC37 fused with Luciferase nanoKAZ. _h[electronic resource] |
| 260 |
_bScientific reports _cAug 2015 |
||
| 300 |
_a12728 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 |
_aBenzofurans _xpharmacology |
| 650 | 0 | 4 |
_aCell Cycle Proteins _xgenetics |
| 650 | 0 | 4 |
_aChaperonins _xgenetics |
| 650 | 0 | 4 |
_aDrug Evaluation, Preclinical _xmethods |
| 650 | 0 | 4 | _aHEK293 Cells |
| 650 | 0 | 4 |
_aHSP90 Heat-Shock Proteins _xgenetics |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aLuciferases _xgenetics |
| 650 | 0 | 4 |
_aMolecular Chaperones _xgenetics |
| 650 | 0 | 4 | _aMutation |
| 650 | 0 | 4 |
_aProtein Kinase Inhibitors _xpharmacology |
| 650 | 0 | 4 |
_aProtein Serine-Threonine Kinases _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aProtein-Tyrosine Kinases _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aRecombinant Fusion Proteins _xgenetics |
| 650 | 0 | 4 |
_aSmall Molecule Libraries _xpharmacology |
| 650 | 0 | 4 |
_aThiazolidines _xpharmacology |
| 650 | 0 | 4 |
_aTriazoles _xpharmacology |
| 650 | 0 | 4 | _aDyrk Kinases |
| 700 | 1 | _aKii, Isao | |
| 700 | 1 | _aKoike, Yuka | |
| 700 | 1 | _aSumida, Yuto | |
| 700 | 1 | _aKato-Sumida, Tomoe | |
| 700 | 1 | _aOkuno, Yukiko | |
| 700 | 1 | _aHosoya, Takamitsu | |
| 700 | 1 | _aHagiwara, Masatoshi | |
| 773 | 0 |
_tScientific reports _gvol. 5 _gp. 12728 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1038/srep12728 _zAvailable from publisher's website |
| 999 |
_c25132119 _d25132119 |
||