| 000 | 02436 a2200661 4500 | ||
|---|---|---|---|
| 005 | 20250517042822.0 | ||
| 264 | 0 | _c20151021 | |
| 008 | 201510s 0 0 eng d | ||
| 022 | _a1872-7980 | ||
| 024 | 7 |
_a10.1016/j.canlet.2015.07.007 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aYu, Zhiyun | |
| 245 | 0 | 0 |
_aNVP-BEZ235, a novel dual PI3K-mTOR inhibitor displays anti-glioma activity and reduces chemoresistance to temozolomide in human glioma cells. _h[electronic resource] |
| 260 |
_bCancer letters _cOct 2015 |
||
| 300 |
_a58-68 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aAntineoplastic Agents, Alkylating _xpharmacology |
| 650 | 0 | 4 |
_aAntineoplastic Combined Chemotherapy Protocols _xpharmacology |
| 650 | 0 | 4 |
_aApoptosis _xdrug effects |
| 650 | 0 | 4 |
_aBrain Neoplasms _xdrug therapy |
| 650 | 0 | 4 |
_aCaspase 3 _xmetabolism |
| 650 | 0 | 4 | _aCell Line, Tumor |
| 650 | 0 | 4 |
_aCell Proliferation _xdrug effects |
| 650 | 0 | 4 |
_aDacarbazine _xanalogs & derivatives |
| 650 | 0 | 4 | _aDose-Response Relationship, Drug |
| 650 | 0 | 4 |
_aDrug Resistance, Neoplasm _xdrug effects |
| 650 | 0 | 4 | _aDrug Synergism |
| 650 | 0 | 4 |
_aG1 Phase Cell Cycle Checkpoints _xdrug effects |
| 650 | 0 | 4 |
_aGlioma _xdrug therapy |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aImidazoles _xpharmacology |
| 650 | 0 | 4 | _aInhibitory Concentration 50 |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 | _aMice, SCID |
| 650 | 0 | 4 |
_aPhosphatidylinositol 3-Kinase _xmetabolism |
| 650 | 0 | 4 | _aPhosphoinositide-3 Kinase Inhibitors |
| 650 | 0 | 4 | _aPhosphorylation |
| 650 | 0 | 4 |
_aProtein Kinase Inhibitors _xpharmacology |
| 650 | 0 | 4 |
_aProto-Oncogene Proteins c-akt _xmetabolism |
| 650 | 0 | 4 |
_aQuinolines _xpharmacology |
| 650 | 0 | 4 |
_aSignal Transduction _xdrug effects |
| 650 | 0 | 4 |
_aTOR Serine-Threonine Kinases _xantagonists & inhibitors |
| 650 | 0 | 4 | _aTemozolomide |
| 650 | 0 | 4 |
_aTumor Burden _xdrug effects |
| 650 | 0 | 4 | _aXenograft Model Antitumor Assays |
| 650 | 0 | 4 |
_abcl-2-Associated X Protein _xmetabolism |
| 700 | 1 | _aXie, Guifang | |
| 700 | 1 | _aZhou, Guangtong | |
| 700 | 1 | _aCheng, Ye | |
| 700 | 1 | _aZhang, Guangtao | |
| 700 | 1 | _aYao, Guangming | |
| 700 | 1 | _aChen, Yong | |
| 700 | 1 | _aLi, Yunqian | |
| 700 | 1 | _aZhao, Gang | |
| 773 | 0 |
_tCancer letters _gvol. 367 _gno. 1 _gp. 58-68 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.canlet.2015.07.007 _zAvailable from publisher's website |
| 999 |
_c25087290 _d25087290 |
||