000 02214 a2200685 4500
005 20250517042502.0
264 0 _c20151006
008 201510s 0 0 eng d
022 _a1521-0103
024 7 _a10.1124/jpet.115.225466
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBonaventure, Pascal
245 0 0 _aCharacterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia.
_h[electronic resource]
260 _bThe Journal of pharmacology and experimental therapeutics
_cSep 2015
300 _a471-82 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnimals
650 0 4 _aBinding Sites
_xdrug effects
650 0 4 _aBrain
_xdrug effects
650 0 4 _aCHO Cells
650 0 4 _aCell Line
650 0 4 _aCricetulus
650 0 4 _aDopamine
_xmetabolism
650 0 4 _aHEK293 Cells
650 0 4 _aHumans
650 0 4 _aHypnotics and Sedatives
_xpharmacology
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Knockout
650 0 4 _aOrexin Receptor Antagonists
650 0 4 _aPyridines
_xpharmacology
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aSleep
_xdrug effects
650 0 4 _aSleep Initiation and Maintenance Disorders
_xdrug therapy
650 0 4 _aSleep Stages
_xdrug effects
650 0 4 _aSleep, REM
_xdrug effects
650 0 4 _aZolpidem
700 1 _aShelton, Jonathan
700 1 _aYun, Sujin
700 1 _aNepomuceno, Diane
700 1 _aSutton, Steven
700 1 _aAluisio, Leah
700 1 _aFraser, Ian
700 1 _aLord, Brian
700 1 _aShoblock, James
700 1 _aWelty, Natalie
700 1 _aChaplan, Sandra R
700 1 _aAguilar, Zuleima
700 1 _aHalter, Robin
700 1 _aNdifor, Anthony
700 1 _aKoudriakova, Tatiana
700 1 _aRizzolio, Michele
700 1 _aLetavic, Michael
700 1 _aCarruthers, Nicholas I
700 1 _aLovenberg, Timothy
700 1 _aDugovic, Christine
773 0 _tThe Journal of pharmacology and experimental therapeutics
_gvol. 354
_gno. 3
_gp. 471-82
856 4 0 _uhttps://doi.org/10.1124/jpet.115.225466
_zAvailable from publisher's website
999 _c25077142
_d25077142