000 01943 a2200505 4500
005 20250517041958.0
264 0 _c20160629
008 201606s 0 0 eng d
022 _a1878-1705
024 7 _a10.1016/j.intimp.2015.06.032
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLi, Wei
245 0 0 _aTanshinone IIA represses inflammatory response and reduces radiculopathic pain by inhibiting IRAK-1 and NF-κB/p38/JNK signaling.
_h[electronic resource]
260 _bInternational immunopharmacology
_cSep 2015
300 _a382-9 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAbietanes
_xpharmacology
650 0 4 _aAnalgesics
_xpharmacology
650 0 4 _aAnimals
650 0 4 _aAnti-Inflammatory Agents, Non-Steroidal
_xpharmacology
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aCells, Cultured
650 0 4 _aCyclooxygenase 2
_xgenetics
650 0 4 _aDrugs, Chinese Herbal
_xpharmacology
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aInterleukin-1 Receptor-Associated Kinases
_xmetabolism
650 0 4 _aInterleukin-1beta
650 0 4 _aIntervertebral Disc
_xcytology
650 0 4 _aIntervertebral Disc Degeneration
_xdrug therapy
650 0 4 _aIntervertebral Disc Displacement
_xdrug therapy
650 0 4 _aJNK Mitogen-Activated Protein Kinases
_xmetabolism
650 0 4 _aMatrix Metalloproteinase 1
_xgenetics
650 0 4 _aMatrix Metalloproteinase 13
_xgenetics
650 0 4 _aNF-kappa B
_xmetabolism
650 0 4 _aNitric Oxide Synthase Type II
_xgenetics
650 0 4 _aPain
_xdrug therapy
650 0 4 _aRats, Sprague-Dawley
650 0 4 _ap38 Mitogen-Activated Protein Kinases
_xmetabolism
700 1 _aZhang, Yu
700 1 _aXing, Cuiyan
700 1 _aZhang, Mengyuan
773 0 _tInternational immunopharmacology
_gvol. 28
_gno. 1
_gp. 382-9
856 4 0 _uhttps://doi.org/10.1016/j.intimp.2015.06.032
_zAvailable from publisher's website
999 _c25063121
_d25063121