000 01747 a2200505 4500
005 20250517041256.0
264 0 _c20160804
008 201608s 0 0 eng d
022 _a2045-2322
024 7 _a10.1038/srep12007
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMoilanen, Anu-Maarit
245 0 0 _aDiscovery of ODM-201, a new-generation androgen receptor inhibitor targeting resistance mechanisms to androgen signaling-directed prostate cancer therapies.
_h[electronic resource]
260 _bScientific reports
_cJul 2015
300 _a12007 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAndrogen Receptor Antagonists
_xpharmacology
650 0 4 _aAndrogens
_xphysiology
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xpharmacokinetics
650 0 4 _aCell Line, Tumor
650 0 4 _aDrug Resistance, Neoplasm
650 0 4 _aHEK293 Cells
650 0 4 _aHumans
650 0 4 _aMale
650 0 4 _aMice, Inbred BALB C
650 0 4 _aMice, Nude
650 0 4 _aProstatic Neoplasms
_xdrug therapy
650 0 4 _aPyrazoles
_xpharmacokinetics
650 0 4 _aReceptors, Androgen
_xmetabolism
650 0 4 _aSignal Transduction
650 0 4 _aTumor Burden
_xdrug effects
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aRiikonen, Reetta
700 1 _aOksala, Riikka
700 1 _aRavanti, Laura
700 1 _aAho, Eija
700 1 _aWohlfahrt, Gerd
700 1 _aNykänen, Pirjo S
700 1 _aTörmäkangas, Olli P
700 1 _aPalvimo, Jorma J
700 1 _aKallio, Pekka J
773 0 _tScientific reports
_gvol. 5
_gp. 12007
856 4 0 _uhttps://doi.org/10.1038/srep12007
_zAvailable from publisher's website
999 _c25040258
_d25040258