000 02089 a2200541 4500
005 20250517041106.0
264 0 _c20160510
008 201605s 0 0 eng d
022 _a1932-6203
024 7 _a10.1371/journal.pone.0132221
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aAlsamarah, Abdelaziz
245 0 0 _aUncovering Molecular Bases Underlying Bone Morphogenetic Protein Receptor Inhibitor Selectivity.
_h[electronic resource]
260 _bPloS one
_c2015
300 _ae0132221 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aActivin Receptors, Type I
_xantagonists & inhibitors
650 0 4 _aAdenosine Triphosphate
_xmetabolism
650 0 4 _aAmino Acid Motifs
650 0 4 _aAmino Acid Substitution
650 0 4 _aBinding Sites
_xdrug effects
650 0 4 _aBone Morphogenetic Protein Receptors, Type I
_xantagonists & inhibitors
650 0 4 _aCrystallography, X-Ray
650 0 4 _aDrug Design
650 0 4 _aHumans
650 0 4 _aLigands
650 0 4 _aMolecular Docking Simulation
650 0 4 _aMolecular Dynamics Simulation
650 0 4 _aMolecular Structure
650 0 4 _aPoint Mutation
650 0 4 _aProtein Conformation
650 0 4 _aProtein Kinase Inhibitors
_xchemistry
650 0 4 _aProtein Serine-Threonine Kinases
_xantagonists & inhibitors
650 0 4 _aProtein Structure, Tertiary
650 0 4 _aPyrazoles
_xchemistry
650 0 4 _aPyrimidines
_xchemistry
650 0 4 _aQuinolines
_xchemistry
650 0 4 _aReceptor, Transforming Growth Factor-beta Type I
650 0 4 _aReceptors, Transforming Growth Factor beta
_xantagonists & inhibitors
650 0 4 _aSubstrate Specificity
650 0 4 _aVascular Endothelial Growth Factor Receptor-2
_xantagonists & inhibitors
700 1 _aLaCuran, Alecander E
700 1 _aOelschlaeger, Peter
700 1 _aHao, Jijun
700 1 _aLuo, Yun
773 0 _tPloS one
_gvol. 10
_gno. 7
_gp. e0132221
856 4 0 _uhttps://doi.org/10.1371/journal.pone.0132221
_zAvailable from publisher's website
999 _c25035999
_d25035999